Actinomycetoma: Difference between revisions
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[[File:Actinomycetoma_before_treatment.tif| | {{SI}} | ||
{{Infobox medical condition | |||
| name = Actinomycetoma | |||
| image = [[File:Actinomycetoma_before_treatment.tif|250px]] | |||
| caption = Actinomycetoma before treatment | |||
| field = [[Infectious disease]] | |||
| synonyms = | |||
| symptoms = [[Swelling]], [[draining sinuses]], [[granules]] | |||
| complications = [[Bone destruction]], [[secondary bacterial infection]] | |||
| onset = Gradual | |||
| duration = Chronic | |||
| causes = [[Actinomycetes]] (e.g., ''[[Nocardia]]'', ''[[Streptomyces]]'') | |||
| risks = [[Trauma]], [[immunosuppression]] | |||
| diagnosis = [[Clinical examination]], [[microscopy]], [[culture]] | |||
| differential = [[Eumycetoma]], [[tuberculosis]], [[chronic osteomyelitis]] | |||
| prevention = Avoidance of trauma, protective footwear | |||
| treatment = [[Antibiotics]] (e.g., [[sulfonamides]], [[aminoglycosides]]) | |||
| medication = | |||
| prognosis = Variable, depends on early diagnosis and treatment | |||
| frequency = More common in [[tropical]] and [[subtropical]] regions | |||
}} | |||
'''Actinomycetoma''' is a chronic [[subcutaneous]] infection caused by [[actinomycetes]], a group of [[bacteria]] that are filamentous and branching. This condition is a type of [[mycetoma]], which is characterized by the formation of [[granulomas]] and abscesses, leading to the destruction of [[tissue]] and [[bone]]. | |||
==Etiology== | ==Etiology== | ||
Actinomycetoma is primarily caused by [[actinomycetes]] such as ''[[Nocardia]]'', ''[[Streptomyces]]'', and ''[[Actinomadura]]''. These organisms are commonly found in soil and decaying organic matter. Infection typically occurs when the skin is punctured by a thorn or splinter, allowing the bacteria to enter the [[subcutaneous tissue]]. | Actinomycetoma is primarily caused by [[actinomycetes]] such as ''[[Nocardia]]'', ''[[Streptomyces]]'', and ''[[Actinomadura]]''. These organisms are commonly found in soil and decaying organic matter. Infection typically occurs when the skin is punctured by a thorn or splinter, allowing the bacteria to enter the [[subcutaneous tissue]]. | ||
==Clinical Features== | ==Clinical Features== | ||
The clinical presentation of actinomycetoma includes: | The clinical presentation of actinomycetoma includes: | ||
| Line 10: | Line 29: | ||
* Discharge of [[serous]] or [[purulent]] material containing [[sulfur granules]] | * Discharge of [[serous]] or [[purulent]] material containing [[sulfur granules]] | ||
* Progressive destruction of [[soft tissue]] and [[bone]] | * Progressive destruction of [[soft tissue]] and [[bone]] | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of actinomycetoma is based on clinical features, [[histopathology]], and [[microbiological]] studies. [[Imaging]] techniques such as [[X-ray]] and [[MRI]] can help assess the extent of tissue and bone involvement. [[Culture]] and [[PCR]] can be used to identify the causative organism. | Diagnosis of actinomycetoma is based on clinical features, [[histopathology]], and [[microbiological]] studies. [[Imaging]] techniques such as [[X-ray]] and [[MRI]] can help assess the extent of tissue and bone involvement. [[Culture]] and [[PCR]] can be used to identify the causative organism. | ||
==Treatment== | ==Treatment== | ||
Treatment of actinomycetoma involves prolonged courses of [[antibiotics]] such as [[sulfonamides]], [[aminoglycosides]], and [[tetracyclines]]. In severe cases, [[surgical debridement]] or [[amputation]] may be necessary to remove infected tissue. | Treatment of actinomycetoma involves prolonged courses of [[antibiotics]] such as [[sulfonamides]], [[aminoglycosides]], and [[tetracyclines]]. In severe cases, [[surgical debridement]] or [[amputation]] may be necessary to remove infected tissue. | ||
==Prevention== | ==Prevention== | ||
Preventive measures include wearing protective clothing and footwear to avoid skin injuries, especially in endemic areas. Prompt cleaning and care of wounds can also reduce the risk of infection. | Preventive measures include wearing protective clothing and footwear to avoid skin injuries, especially in endemic areas. Prompt cleaning and care of wounds can also reduce the risk of infection. | ||
==Epidemiology== | ==Epidemiology== | ||
Actinomycetoma is more common in tropical and subtropical regions, particularly in countries with a high prevalence of [[agriculture]] and [[outdoor activities]]. It affects individuals of all ages but is more common in adult males. | Actinomycetoma is more common in tropical and subtropical regions, particularly in countries with a high prevalence of [[agriculture]] and [[outdoor activities]]. It affects individuals of all ages but is more common in adult males. | ||
==See Also== | ==See Also== | ||
* [[Mycetoma]] | * [[Mycetoma]] | ||
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* [[Actinomadura]] | * [[Actinomadura]] | ||
* [[Subcutaneous infection]] | * [[Subcutaneous infection]] | ||
==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
==External Links== | ==External Links== | ||
{{Commons category|Actinomycetoma}} | {{Commons category|Actinomycetoma}} | ||
[[Category:Infectious diseases]] | [[Category:Infectious diseases]] | ||
[[Category:Bacterial diseases]] | [[Category:Bacterial diseases]] | ||
| Line 41: | Line 52: | ||
[[Category:Tropical diseases]] | [[Category:Tropical diseases]] | ||
[[Category:Neglected tropical diseases]] | [[Category:Neglected tropical diseases]] | ||
{{Infectious disease-stub}} | {{Infectious disease-stub}} | ||
Latest revision as of 21:56, 5 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Actinomycetoma | |
|---|---|
| |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Swelling, draining sinuses, granules |
| Complications | Bone destruction, secondary bacterial infection |
| Onset | Gradual |
| Duration | Chronic |
| Types | N/A |
| Causes | Actinomycetes (e.g., Nocardia, Streptomyces) |
| Risks | Trauma, immunosuppression |
| Diagnosis | Clinical examination, microscopy, culture |
| Differential diagnosis | Eumycetoma, tuberculosis, chronic osteomyelitis |
| Prevention | Avoidance of trauma, protective footwear |
| Treatment | Antibiotics (e.g., sulfonamides, aminoglycosides) |
| Medication | |
| Prognosis | Variable, depends on early diagnosis and treatment |
| Frequency | More common in tropical and subtropical regions |
| Deaths | N/A |
Actinomycetoma is a chronic subcutaneous infection caused by actinomycetes, a group of bacteria that are filamentous and branching. This condition is a type of mycetoma, which is characterized by the formation of granulomas and abscesses, leading to the destruction of tissue and bone.
Etiology[edit]
Actinomycetoma is primarily caused by actinomycetes such as Nocardia, Streptomyces, and Actinomadura. These organisms are commonly found in soil and decaying organic matter. Infection typically occurs when the skin is punctured by a thorn or splinter, allowing the bacteria to enter the subcutaneous tissue.
Clinical Features[edit]
The clinical presentation of actinomycetoma includes:
- Swelling of the affected area
- Formation of multiple sinus tracts
- Discharge of serous or purulent material containing sulfur granules
- Progressive destruction of soft tissue and bone
Diagnosis[edit]
Diagnosis of actinomycetoma is based on clinical features, histopathology, and microbiological studies. Imaging techniques such as X-ray and MRI can help assess the extent of tissue and bone involvement. Culture and PCR can be used to identify the causative organism.
Treatment[edit]
Treatment of actinomycetoma involves prolonged courses of antibiotics such as sulfonamides, aminoglycosides, and tetracyclines. In severe cases, surgical debridement or amputation may be necessary to remove infected tissue.
Prevention[edit]
Preventive measures include wearing protective clothing and footwear to avoid skin injuries, especially in endemic areas. Prompt cleaning and care of wounds can also reduce the risk of infection.
Epidemiology[edit]
Actinomycetoma is more common in tropical and subtropical regions, particularly in countries with a high prevalence of agriculture and outdoor activities. It affects individuals of all ages but is more common in adult males.
See Also[edit]
References[edit]
<references group="" responsive="1"></references>
External Links[edit]
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