Renal osteodystrophy: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Renal osteodystrophy | |||
| image = [[File:X-ray_of_periosteal_reaction_in_renal_osteodystrophy.jpg|250px]] | |||
| caption = X-ray showing periosteal reaction in renal osteodystrophy | |||
| field = [[Nephrology]] / [[Endocrinology]] | |||
| synonyms = | |||
| symptoms = Bone pain, skeletal deformities, fractures | |||
| complications = [[Fracture]], [[vascular calcification]] | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = [[Chronic kidney disease]], [[secondary hyperparathyroidism]] | |||
| risks = | |||
| diagnosis = [[Blood test]], [[X-ray]], [[bone biopsy]] | |||
| differential = [[Osteoporosis]], [[osteomalacia]] | |||
| prevention = | |||
| treatment = [[Phosphate binders]], [[vitamin D]] analogs, [[parathyroidectomy]] | |||
| medication = | |||
| prognosis = | |||
| frequency = Common in patients with [[chronic kidney disease]] | |||
| deaths = | |||
}} | |||
'''Renal osteodystrophy''' is a [[bone disease]] that occurs when your [[kidneys]] fail to maintain the proper levels of [[calcium]] and [[phosphorus]] in your blood. It's a common problem in people with [[kidney disease]] and affects almost all patients at some stage of chronic kidney disease. | '''Renal osteodystrophy''' is a [[bone disease]] that occurs when your [[kidneys]] fail to maintain the proper levels of [[calcium]] and [[phosphorus]] in your blood. It's a common problem in people with [[kidney disease]] and affects almost all patients at some stage of chronic kidney disease. | ||
== Causes == | == Causes == | ||
Renal osteodystrophy is caused by changes in the [[hormones]] that maintain calcium and phosphorus balance. The kidneys convert [[vitamin D]] from the skin and diet into an active form that helps the body absorb calcium from the intestines. In kidney disease, this conversion is reduced, leading to lower calcium levels. In response, the [[parathyroid glands]] produce more [[parathyroid hormone]] (PTH), which helps restore calcium levels by reabsorption from the bones. However, this can lead to bone disease. | Renal osteodystrophy is caused by changes in the [[hormones]] that maintain calcium and phosphorus balance. The kidneys convert [[vitamin D]] from the skin and diet into an active form that helps the body absorb calcium from the intestines. In kidney disease, this conversion is reduced, leading to lower calcium levels. In response, the [[parathyroid glands]] produce more [[parathyroid hormone]] (PTH), which helps restore calcium levels by reabsorption from the bones. However, this can lead to bone disease. | ||
== Symptoms == | == Symptoms == | ||
Symptoms of renal osteodystrophy can vary. Some people have no symptoms, while others may experience [[bone pain]], [[joint pain]], fractures, and [[muscle weakness]]. In children, the disease can cause growth retardation and bone deformities. | Symptoms of renal osteodystrophy can vary. Some people have no symptoms, while others may experience [[bone pain]], [[joint pain]], fractures, and [[muscle weakness]]. In children, the disease can cause growth retardation and bone deformities. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of renal osteodystrophy involves blood tests to measure levels of calcium, phosphorus, PTH, and vitamin D. [[Bone biopsy]] may also be performed to assess the type and severity of the disease. | Diagnosis of renal osteodystrophy involves blood tests to measure levels of calcium, phosphorus, PTH, and vitamin D. [[Bone biopsy]] may also be performed to assess the type and severity of the disease. | ||
== Treatment == | == Treatment == | ||
Treatment aims to restore the balance of calcium, phosphorus, and PTH. This may involve dietary changes, medications to lower phosphorus levels, vitamin D supplements, and in some cases, surgery to remove the parathyroid glands. | Treatment aims to restore the balance of calcium, phosphorus, and PTH. This may involve dietary changes, medications to lower phosphorus levels, vitamin D supplements, and in some cases, surgery to remove the parathyroid glands. | ||
==Gallery== | |||
<gallery> | |||
File:X-ray of ground glass density of the skull by renal osteodystrophy.jpg|Renal osteodystrophy | |||
File:CT of sclerotic lesions in the skull in renal osteodystrophy.jpg|Renal osteodystrophy | |||
File:X-ray of brown tumors in the pelvis and a hip fracture in renal osteodystrophy.jpg|Renal osteodystrophy | |||
File:CT of subchondral resorption in the SI joint in renal osteodystrophy.jpg|Renal osteodystrophy | |||
File:X-ray of rugger-jersey spine of renal osteodystrophy.jpg|Renal osteodystrophy | |||
File:CT of rugger-jersey spine of renal osteodystrophy.jpg|Renal osteodystrophy | |||
</gallery> | |||
== See also == | == See also == | ||
* [[Chronic kidney disease]] | * [[Chronic kidney disease]] | ||
* [[Bone disease]] | * [[Bone disease]] | ||
* [[Parathyroid hormone]] | * [[Parathyroid hormone]] | ||
* [[Vitamin D]] | * [[Vitamin D]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Bone diseases]] | [[Category:Bone diseases]] | ||
[[Category:Kidney diseases]] | [[Category:Kidney diseases]] | ||
[[Category:Endocrine diseases]] | [[Category:Endocrine diseases]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 06:33, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Renal osteodystrophy | |
|---|---|
| |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Bone pain, skeletal deformities, fractures |
| Complications | Fracture, vascular calcification |
| Onset | |
| Duration | |
| Types | |
| Causes | Chronic kidney disease, secondary hyperparathyroidism |
| Risks | |
| Diagnosis | Blood test, X-ray, bone biopsy |
| Differential diagnosis | Osteoporosis, osteomalacia |
| Prevention | |
| Treatment | Phosphate binders, vitamin D analogs, parathyroidectomy |
| Medication | |
| Prognosis | |
| Frequency | Common in patients with chronic kidney disease |
| Deaths | |
Renal osteodystrophy is a bone disease that occurs when your kidneys fail to maintain the proper levels of calcium and phosphorus in your blood. It's a common problem in people with kidney disease and affects almost all patients at some stage of chronic kidney disease.
Causes[edit]
Renal osteodystrophy is caused by changes in the hormones that maintain calcium and phosphorus balance. The kidneys convert vitamin D from the skin and diet into an active form that helps the body absorb calcium from the intestines. In kidney disease, this conversion is reduced, leading to lower calcium levels. In response, the parathyroid glands produce more parathyroid hormone (PTH), which helps restore calcium levels by reabsorption from the bones. However, this can lead to bone disease.
Symptoms[edit]
Symptoms of renal osteodystrophy can vary. Some people have no symptoms, while others may experience bone pain, joint pain, fractures, and muscle weakness. In children, the disease can cause growth retardation and bone deformities.
Diagnosis[edit]
Diagnosis of renal osteodystrophy involves blood tests to measure levels of calcium, phosphorus, PTH, and vitamin D. Bone biopsy may also be performed to assess the type and severity of the disease.
Treatment[edit]
Treatment aims to restore the balance of calcium, phosphorus, and PTH. This may involve dietary changes, medications to lower phosphorus levels, vitamin D supplements, and in some cases, surgery to remove the parathyroid glands.
Gallery[edit]
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Renal osteodystrophy -
Renal osteodystrophy -
Renal osteodystrophy -
Renal osteodystrophy -
Renal osteodystrophy -
Renal osteodystrophy
See also[edit]
References[edit]
<references />
