Mantleoma: Difference between revisions
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{{Infobox medical condition | |||
| name = Mantleoma | |||
| synonyms = [[Mantle cell lymphoma]] | |||
| field = [[Hematology]] | |||
| symptoms = [[Lymphadenopathy]], [[fever]], [[night sweats]], [[weight loss]] | |||
| complications = [[Bone marrow failure]], [[splenomegaly]] | |||
| onset = Typically in [[middle-aged]] to [[older adults]] | |||
| duration = Chronic | |||
| causes = [[Genetic mutations]], [[chromosomal translocations]] | |||
| risks = [[Age]], [[male gender]], [[family history]] | |||
| diagnosis = [[Biopsy]], [[immunohistochemistry]], [[flow cytometry]] | |||
| differential = [[Chronic lymphocytic leukemia]], [[diffuse large B-cell lymphoma]] | |||
| treatment = [[Chemotherapy]], [[immunotherapy]], [[stem cell transplant]] | |||
| prognosis = Variable, often poor | |||
| frequency = Rare, approximately 6% of [[non-Hodgkin lymphoma]] cases | |||
}} | |||
'''Mantleoma''' is a rare type of [[cancer]] that originates from the [[mantle cell]]s of the [[lymphatic system]]. This type of cancer is characterized by the uncontrolled growth and spread of abnormal cells in the mantle zone of the lymph nodes. | '''Mantleoma''' is a rare type of [[cancer]] that originates from the [[mantle cell]]s of the [[lymphatic system]]. This type of cancer is characterized by the uncontrolled growth and spread of abnormal cells in the mantle zone of the lymph nodes. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of mantleoma can vary depending on the stage of the disease and the individual's overall health. Common symptoms may include: | The symptoms of mantleoma can vary depending on the stage of the disease and the individual's overall health. Common symptoms may include: | ||
* [[Fatigue]] | * [[Fatigue]] | ||
* [[Fever]] | * [[Fever]] | ||
| Line 10: | Line 24: | ||
* [[Weight loss]] | * [[Weight loss]] | ||
* [[Swollen lymph nodes]] | * [[Swollen lymph nodes]] | ||
== Causes == | == Causes == | ||
The exact cause of mantleoma is unknown. However, it is believed to be associated with a genetic mutation in the [[cyclin D1]] gene. This mutation leads to the overproduction of cyclin D1 protein, which promotes cell growth and division. | The exact cause of mantleoma is unknown. However, it is believed to be associated with a genetic mutation in the [[cyclin D1]] gene. This mutation leads to the overproduction of cyclin D1 protein, which promotes cell growth and division. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of mantleoma typically involves a combination of physical examination, medical history, and laboratory tests. These may include: | Diagnosis of mantleoma typically involves a combination of physical examination, medical history, and laboratory tests. These may include: | ||
* [[Biopsy]] of the affected lymph node | * [[Biopsy]] of the affected lymph node | ||
* [[Blood tests]] | * [[Blood tests]] | ||
* [[Imaging tests]] such as [[CT scan]] or [[MRI]] | * [[Imaging tests]] such as [[CT scan]] or [[MRI]] | ||
* [[Bone marrow biopsy]] | * [[Bone marrow biopsy]] | ||
== Treatment == | == Treatment == | ||
Treatment for mantleoma depends on the stage of the disease, the patient's overall health, and their personal preferences. Treatment options may include: | Treatment for mantleoma depends on the stage of the disease, the patient's overall health, and their personal preferences. Treatment options may include: | ||
* [[Chemotherapy]] | * [[Chemotherapy]] | ||
* [[Radiation therapy]] | * [[Radiation therapy]] | ||
| Line 33: | Line 39: | ||
* [[Immunotherapy]] | * [[Immunotherapy]] | ||
* [[Targeted therapy]] | * [[Targeted therapy]] | ||
== Prognosis == | == Prognosis == | ||
The prognosis for individuals with mantleoma varies widely. Factors that can affect prognosis include the stage of the disease at diagnosis, the individual's overall health, and the response to treatment. | The prognosis for individuals with mantleoma varies widely. Factors that can affect prognosis include the stage of the disease at diagnosis, the individual's overall health, and the response to treatment. | ||
== See also == | == See also == | ||
* [[Lymphoma]] | * [[Lymphoma]] | ||
* [[Non-Hodgkin lymphoma]] | * [[Non-Hodgkin lymphoma]] | ||
* [[Cancer]] | * [[Cancer]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Cancer]] | [[Category:Cancer]] | ||
[[Category:Lymphoma]] | [[Category:Lymphoma]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | |||
Latest revision as of 00:52, 4 April 2025
| Mantleoma | |
|---|---|
| Synonyms | Mantle cell lymphoma |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Lymphadenopathy, fever, night sweats, weight loss |
| Complications | Bone marrow failure, splenomegaly |
| Onset | Typically in middle-aged to older adults |
| Duration | Chronic |
| Types | N/A |
| Causes | Genetic mutations, chromosomal translocations |
| Risks | Age, male gender, family history |
| Diagnosis | Biopsy, immunohistochemistry, flow cytometry |
| Differential diagnosis | Chronic lymphocytic leukemia, diffuse large B-cell lymphoma |
| Prevention | N/A |
| Treatment | Chemotherapy, immunotherapy, stem cell transplant |
| Medication | N/A |
| Prognosis | Variable, often poor |
| Frequency | Rare, approximately 6% of non-Hodgkin lymphoma cases |
| Deaths | N/A |
Mantleoma is a rare type of cancer that originates from the mantle cells of the lymphatic system. This type of cancer is characterized by the uncontrolled growth and spread of abnormal cells in the mantle zone of the lymph nodes.
Symptoms[edit]
The symptoms of mantleoma can vary depending on the stage of the disease and the individual's overall health. Common symptoms may include:
Causes[edit]
The exact cause of mantleoma is unknown. However, it is believed to be associated with a genetic mutation in the cyclin D1 gene. This mutation leads to the overproduction of cyclin D1 protein, which promotes cell growth and division.
Diagnosis[edit]
Diagnosis of mantleoma typically involves a combination of physical examination, medical history, and laboratory tests. These may include:
- Biopsy of the affected lymph node
- Blood tests
- Imaging tests such as CT scan or MRI
- Bone marrow biopsy
Treatment[edit]
Treatment for mantleoma depends on the stage of the disease, the patient's overall health, and their personal preferences. Treatment options may include:
Prognosis[edit]
The prognosis for individuals with mantleoma varies widely. Factors that can affect prognosis include the stage of the disease at diagnosis, the individual's overall health, and the response to treatment.
See also[edit]
References[edit]
<references />
