Estradiol valerate/prasterone enanthate

Estradiol valerate/prasterone enanthate (EV/DHEA-E), sold under the brand name Gynodian Depot, is a medication which is used in hormone therapy for menopausal symptoms and low sex hormone levels in women. It is a combination of estradiol valerate, an estrogen, and prasterone enanthate (DHEA-E), an androgen.

Pharmacology

Estradiol valerate/prasterone enanthate is a combination medication of estradiol valerate, an estrogen, and prasterone enanthate, an androgen. The medication is administered by intramuscular injection.

Estradiol valerate

Estradiol valerate is a synthetic ester of the natural estrogen, estradiol. It is one of several esters of estradiol that are used in hormone therapy. Estradiol valerate is converted in the body to estradiol.

Prasterone enanthate

Prasterone enanthate is a synthetic ester of the natural androgen, dehydroepiandrosterone (DHEA). It is one of several esters of DHEA that are used in hormone therapy. Prasterone enanthate is converted in the body to DHEA.

Clinical use

Estradiol valerate/prasterone enanthate is used in hormone therapy for menopausal symptoms and low sex hormone levels in women. It is administered by intramuscular injection.

Side effects

Possible side effects of estradiol valerate/prasterone enanthate include menstrual irregularities, breast tenderness, nausea, and headache.

See also

• List of combined sex-hormonal preparations

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Estradiol valerate/prasterone enanthate

• Estradiol and dehydroepiandrosterone levels after a single intramuscular injection of Gynodian Depot in women
  Estradiol and dehydroepiandrosterone levels after a single intramuscular injection of Gynodian Depot in women