Insulin degludec/insulin aspart: Difference between revisions

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'''Insulin degludec/insulin aspart''' is a combination medication used to treat high blood sugar levels caused by type 1 and type 2 diabetes. It is a mixture of insulin degludec, a long-acting insulin, and insulin aspart, a rapid-acting insulin. This combination allows for better blood sugar control throughout the day and night.


==Composition==
{{Short description|Combination insulin medication}}
[[Insulin degludec]] is a long-acting insulin analog that provides a steady level of insulin over a 24-hour period. It is designed to mimic the body's natural insulin release pattern. [[Insulin aspart]] is a rapid-acting insulin analog that begins to work quickly after injection to help manage blood sugar levels at meal times.
{{Infobox drug
| name = Insulin degludec/insulin aspart
| type = combo
| image = <!-- Image removed -->
| caption = <!-- Caption removed -->
| component1 = [[Insulin degludec]]
| class1 = [[Long-acting insulin]]
| component2 = [[Insulin aspart]]
| class2 = [[Rapid-acting insulin]]
| tradename = Ryzodeg
| routes_of_administration = [[Subcutaneous injection]]
| atc_prefix = A10
| atc_suffix = AE06
| legal_status = Rx-only
| pregnancy_category = C
| cas_number = 1260291-89-5
| drugbank = DB06655
| kegg = D10310
}}


==Usage==
'''Insulin degludec/insulin aspart''' is a [[combination medication]] used in the management of [[diabetes mellitus]]. It is a mixture of two types of insulin: [[insulin degludec]], a [[long-acting insulin]], and [[insulin aspart]], a [[rapid-acting insulin]]. This combination is marketed under the brand name '''Ryzodeg'''.
Insulin degludec/insulin aspart is used to improve blood sugar control in adults with diabetes mellitus. It is typically used in combination with a healthy diet and regular exercise. The medication is injected under the skin, usually once a day at the same time each day.


==Side Effects==
==Medical uses==
Possible side effects of insulin degludec/insulin aspart include low blood sugar (hypoglycemia), allergic reactions, injection site reactions, and weight gain. Severe, life-threatening allergic reactions are rare but can occur.
Insulin degludec/insulin aspart is indicated for the treatment of [[type 1 diabetes]] and [[type 2 diabetes]] in adults. It helps to control [[blood glucose levels]] by providing both basal and prandial insulin coverage.


==Precautions==
==Mechanism of action==
Before starting insulin degludec/insulin aspart, patients should inform their healthcare provider about all their medical conditions, including if they have liver or kidney problems, are pregnant or planning to become pregnant, or are breastfeeding or planning to breastfeed.
The combination of insulin degludec and insulin aspart works by mimicking the body's natural pattern of insulin release. [[Insulin degludec]] provides a steady, long-lasting insulin level, while [[insulin aspart]] offers a rapid onset of action to manage blood sugar spikes after meals.


==Pharmacology==
==Administration==
Insulin degludec/insulin aspart works by replacing the insulin that is normally produced by the body and by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar.
The medication is administered via [[subcutaneous injection]]. The dosing schedule is typically individualized based on the patient's needs, blood glucose monitoring results, and glycemic control goals.


[[File:Insulin degludec.jpg|thumb|Chemical structure of insulin degludec]]
==Side effects==
[[File:Insulin aspart.jpg|thumb|Chemical structure of insulin aspart]]
Common side effects include [[hypoglycemia]], [[allergic reactions]], and [[injection site reactions]]. Patients should be monitored for signs of low blood sugar and other adverse effects.


==See Also==
==See also==
* [[Insulin therapy]]
* [[Insulin therapy]]
* [[Diabetes management]]
* [[Diabetes management]]
* [[Hypoglycemia]]


[[Category:Diabetes]]
==References==
[[Category:Insulin]]
{{Reflist}}
[[Category:Medications]]
 
==External links==
* [https://www.wikimd.com/wiki/Insulin_degludec/insulin_aspart Insulin degludec/insulin aspart on WikiMD]
 
[[Category:Combination drugs]]
[[Category:Insulin therapies]]
[[Category:Diabetes treatments]]

Latest revision as of 04:37, 29 December 2024


Combination insulin medication


Insulin degludec/insulin aspart
[[File:|frameless|220px|alt=|]]
INN
Drug class
Routes of administration Subcutaneous injection
Pregnancy category C
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status Rx-only
CAS Number
PubChem
DrugBank
ChemSpider
KEGG


Insulin degludec/insulin aspart is a combination medication used in the management of diabetes mellitus. It is a mixture of two types of insulin: insulin degludec, a long-acting insulin, and insulin aspart, a rapid-acting insulin. This combination is marketed under the brand name Ryzodeg.

Medical uses[edit]

Insulin degludec/insulin aspart is indicated for the treatment of type 1 diabetes and type 2 diabetes in adults. It helps to control blood glucose levels by providing both basal and prandial insulin coverage.

Mechanism of action[edit]

The combination of insulin degludec and insulin aspart works by mimicking the body's natural pattern of insulin release. Insulin degludec provides a steady, long-lasting insulin level, while insulin aspart offers a rapid onset of action to manage blood sugar spikes after meals.

Administration[edit]

The medication is administered via subcutaneous injection. The dosing schedule is typically individualized based on the patient's needs, blood glucose monitoring results, and glycemic control goals.

Side effects[edit]

Common side effects include hypoglycemia, allergic reactions, and injection site reactions. Patients should be monitored for signs of low blood sugar and other adverse effects.

See also[edit]

References[edit]

<references group="" responsive="1"></references>


External links[edit]