Latent tuberculosis: Difference between revisions
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== | {{SI}} | ||
{{Infobox medical condition | |||
| name = Latent tuberculosis | |||
| image = [[File:Teoria_de_la_Coalescència.jpg|250px]] | |||
| caption = | |||
| field = [[Infectious disease]] | |||
| synonyms = | |||
| symptoms = None | |||
| complications = [[Tuberculosis]] | |||
| onset = | |||
| duration = | |||
| causes = [[Mycobacterium tuberculosis]] | |||
| risks = [[HIV/AIDS]], [[immunosuppression]], [[malnutrition]] | |||
| diagnosis = [[Tuberculin skin test]], [[Interferon gamma release assay]] | |||
| differential = | |||
| prevention = [[BCG vaccine]], [[treatment of latent tuberculosis]] | |||
| treatment = [[Isoniazid]], [[Rifampin]], [[Rifapentine]] | |||
| medication = | |||
| prognosis = | |||
| frequency = | |||
| deaths = | |||
}} | |||
'''Latent tuberculosis''' (LTB) refers to a state in which the ''Mycobacterium tuberculosis'' bacteria are present in the body but remain inactive. People with latent TB do not exhibit symptoms and are not contagious. However, they are at risk of developing active tuberculosis if their immune system weakens. | '''Latent tuberculosis''' (LTB) refers to a state in which the ''Mycobacterium tuberculosis'' bacteria are present in the body but remain inactive. People with latent TB do not exhibit symptoms and are not contagious. However, they are at risk of developing active tuberculosis if their immune system weakens. | ||
== Understanding Latent Tuberculosis == | == Understanding Latent Tuberculosis == | ||
When an individual is exposed to ''Mycobacterium tuberculosis'', their immune system may successfully contain the bacteria, preventing them from multiplying and causing an active infection. This results in latent TB. | When an individual is exposed to ''Mycobacterium tuberculosis'', their immune system may successfully contain the bacteria, preventing them from multiplying and causing an active infection. This results in latent TB. | ||
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=== Distinguishing Features === | === Distinguishing Features === | ||
* '''No Symptoms''': Those with latent TB exhibit no signs or symptoms related to the disease. | * '''No Symptoms''': Those with latent TB exhibit no signs or symptoms related to the disease. | ||
* '''Non-Contagious''': They cannot spread the TB bacteria to others. | * '''Non-Contagious''': They cannot spread the TB bacteria to others. | ||
* '''Potential for Activation''': Without treatment, latent TB can activate, especially in those with compromised immune systems. | * '''Potential for Activation''': Without treatment, latent TB can activate, especially in those with compromised immune systems. | ||
== Diagnosis and Testing == | == Diagnosis and Testing == | ||
A [[Tuberculin skin test]] (TST) or a TB blood test can help determine the presence of latent TB. While these tests show if a person has been infected with the bacteria, they don't differentiate between latent and active TB. Further tests, like chest X-rays, are essential if the initial tests are positive. | A [[Tuberculin skin test]] (TST) or a TB blood test can help determine the presence of latent TB. While these tests show if a person has been infected with the bacteria, they don't differentiate between latent and active TB. Further tests, like chest X-rays, are essential if the initial tests are positive. | ||
[[File:Mantoux tuberculin skin test.jpg|thumb|left|350px|A positive tuberculin skin test indicates exposure to TB bacteria.]] | [[File:Mantoux tuberculin skin test.jpg|thumb|left|350px|A positive tuberculin skin test indicates exposure to TB bacteria.]] | ||
== Treatment and Prevention == | == Treatment and Prevention == | ||
While not everyone with latent TB requires treatment, many at-risk populations benefit from preventative therapy to reduce the likelihood of TB activation. | While not everyone with latent TB requires treatment, many at-risk populations benefit from preventative therapy to reduce the likelihood of TB activation. | ||
=== Medications === | === Medications === | ||
Several medications, such as Isoniazid and Rifapentine, can be prescribed to treat latent TB. It's crucial to follow the full course of treatment to prevent the development of drug-resistant strains of the bacteria. | Several medications, such as Isoniazid and Rifapentine, can be prescribed to treat latent TB. It's crucial to follow the full course of treatment to prevent the development of drug-resistant strains of the bacteria. | ||
== Risk Factors for Activation == | == Risk Factors for Activation == | ||
Certain conditions and factors increase the risk of latent TB becoming active: | Certain conditions and factors increase the risk of latent TB becoming active: | ||
* HIV/AIDS | * HIV/AIDS | ||
* Diabetes | * Diabetes | ||
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* Certain cancers | * Certain cancers | ||
* Medications that suppress the immune system | * Medications that suppress the immune system | ||
== Conclusion == | == Conclusion == | ||
While latent tuberculosis poses a silent threat, understanding, early detection, and treatment are essential steps in preventing the progression to active TB and further spread of this age-old disease. | While latent tuberculosis poses a silent threat, understanding, early detection, and treatment are essential steps in preventing the progression to active TB and further spread of this age-old disease. | ||
[[Category: Diseases and Disorders|Tuberculosis]] | [[Category: Diseases and Disorders|Tuberculosis]] | ||
[[Category: Bacterial Infections|Tuberculosis]] | [[Category: Bacterial Infections|Tuberculosis]] | ||
[[Category:Dictionary of medicine]]. | [[Category:Dictionary of medicine]]. | ||
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Latest revision as of 03:27, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Latent tuberculosis | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | None |
| Complications | Tuberculosis |
| Onset | |
| Duration | |
| Types | N/A |
| Causes | Mycobacterium tuberculosis |
| Risks | HIV/AIDS, immunosuppression, malnutrition |
| Diagnosis | Tuberculin skin test, Interferon gamma release assay |
| Differential diagnosis | |
| Prevention | BCG vaccine, treatment of latent tuberculosis |
| Treatment | Isoniazid, Rifampin, Rifapentine |
| Medication | |
| Prognosis | |
| Frequency | |
| Deaths | |
Latent tuberculosis (LTB) refers to a state in which the Mycobacterium tuberculosis bacteria are present in the body but remain inactive. People with latent TB do not exhibit symptoms and are not contagious. However, they are at risk of developing active tuberculosis if their immune system weakens.
Understanding Latent Tuberculosis[edit]
When an individual is exposed to Mycobacterium tuberculosis, their immune system may successfully contain the bacteria, preventing them from multiplying and causing an active infection. This results in latent TB.
Distinguishing Features[edit]
- No Symptoms: Those with latent TB exhibit no signs or symptoms related to the disease.
- Non-Contagious: They cannot spread the TB bacteria to others.
- Potential for Activation: Without treatment, latent TB can activate, especially in those with compromised immune systems.
Diagnosis and Testing[edit]
A Tuberculin skin test (TST) or a TB blood test can help determine the presence of latent TB. While these tests show if a person has been infected with the bacteria, they don't differentiate between latent and active TB. Further tests, like chest X-rays, are essential if the initial tests are positive.

Treatment and Prevention[edit]
While not everyone with latent TB requires treatment, many at-risk populations benefit from preventative therapy to reduce the likelihood of TB activation.
Medications[edit]
Several medications, such as Isoniazid and Rifapentine, can be prescribed to treat latent TB. It's crucial to follow the full course of treatment to prevent the development of drug-resistant strains of the bacteria.
Risk Factors for Activation[edit]
Certain conditions and factors increase the risk of latent TB becoming active:
- HIV/AIDS
- Diabetes
- Severe kidney disease
- Certain cancers
- Medications that suppress the immune system
Conclusion[edit]
While latent tuberculosis poses a silent threat, understanding, early detection, and treatment are essential steps in preventing the progression to active TB and further spread of this age-old disease..


