Vasitis nodosa: Difference between revisions

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{{Infobox medical condition (new)
{{SI}}
{{Infobox medical condition
| name            = Vasitis nodosa
| name            = Vasitis nodosa
| image          = [[File:Vasitis_nodosa_-11-_intermed_mag.jpg|left|thumb|Vasitis nodosa under intermediate magnification]]
| caption        = Histological image of vasitis nodosa
| field          = [[Urology]]
| synonyms        =  
| synonyms        =  
| image          = Vasitis_nodosa_-11-_intermed_mag.jpg
| symptoms        = Usually asymptomatic, may present as a scrotal mass
| width          =
| complications  = Rarely, can be mistaken for [[vas deferens]] tumors
| caption        = [[Micrograph]] of vasitis nodosa (left of image). [[H&E stain]].
| pronounce      =
| field          = [[Urology]]
| symptoms        =
| complications  =
| onset          =  
| onset          =  
| duration        =  
| duration        =  
| types          =  
| types          =  
| causes          =  
| causes          = [[Surgical]] procedures such as [[vasectomy]]
| risks          =  
| risks          =  
| diagnosis      =  
| diagnosis      = [[Histopathology]]
| differential    =  
| differential    = [[Sperm granuloma]], [[epididymitis]], [[testicular cancer]]
| prevention      =  
| prevention      =  
| treatment      =  
| treatment      = Usually none required
| medication      =  
| medication      =  
| prognosis      =  
| prognosis      = Excellent
| frequency      =  
| frequency      = Common after vasectomy
| deaths          =
}}
}}
'''Vasitis nodosa''' is a [[complication (medicine)|complication]] experienced in approximately 66% of men who undergo [[vasectomy]].<ref name=Taxy>{{cite journal |vauthors=Taxy JB, Marshall FF, Erlichman RJ |title=Vasectomy: subclinical pathologic changes |journal=Am. J. Surg. Pathol. |volume=5 |issue=8 |pages=767–72 |date=December 1981 |pmid=7337163 |doi= 10.1097/00000478-198112000-00005|url=}}</ref> It is a [[Benignity|benign]] [[nodule (medicine)|nodular]] thickening of the [[vas deferens]], in which small offshoots proliferate, infiltrating surrounding tissue.<ref name=Hirsch>{{cite journal |vauthors=Hirschowitz L, Rode J, Guillebaud J, Bounds W, Moss E |title=Vasitis nodosa and associated clinical findings |journal=J. Clin. Pathol. |volume=41 |issue=4 |pages=419–23 |date=April 1988 |pmid=3366928 |pmc=1141468 |doi= 10.1136/jcp.41.4.419|url=http://jcp.bmj.com/cgi/pmidlookup?view=long&pmid=3366928}}</ref>  It can be mistaken for low-grade [[adenocarcinoma]] by [[pathologists]],<ref name=Desh>{{cite journal |vauthors=Deshpande RB, Deshpande J, Mali BN, Kinare SG |title=Vasitis nodosa (a report of 7 cases) |journal=J Postgrad Med |volume=31 |issue=2 |pages=105–8 |date=April 1985 |pmid=4057111 |doi= |url= http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1985;volume=31;issue=2;spage=105;epage=8;aulast=Deshpande }}</ref> and is implicated in late vasectomy failure.<ref name=Hirsch />
{{Short description|A benign condition of the vas deferens}}
 
'''Vasitis nodosa''' is a benign condition affecting the [[vas deferens]], the duct that conveys sperm from the [[epididymis]] to the [[ejaculatory duct]]. It is characterized by the presence of small nodular lesions along the vas deferens, often resulting from previous [[vasectomy]] procedures.
==Pathophysiology==
Vasitis nodosa occurs due to the proliferation of [[epithelial cells]] and [[smooth muscle]] in the vas deferens. This proliferation is typically a response to trauma or surgical intervention, such as a vasectomy. The nodules are composed of hyperplastic tissue, which can sometimes be mistaken for [[malignant]] growths, although vasitis nodosa is entirely benign.
==Clinical Presentation==
Most individuals with vasitis nodosa are asymptomatic and the condition is often discovered incidentally during [[histological]] examination following a vasectomy reversal or other surgical procedures involving the vas deferens. In rare cases, patients may experience discomfort or pain in the scrotal region.
==Diagnosis==
Diagnosis of vasitis nodosa is primarily made through histological examination. The nodules are identified by their characteristic appearance under a microscope, showing proliferation of epithelial and smooth muscle cells. Imaging studies are not typically used for diagnosis.
==Treatment==
Vasitis nodosa does not usually require treatment, as it is a benign condition. In cases where it causes discomfort or is mistaken for a malignant condition, surgical intervention may be considered. However, this is rare.
==Prognosis==
The prognosis for individuals with vasitis nodosa is excellent, as the condition is benign and does not affect fertility or overall health. It is important for healthcare providers to distinguish vasitis nodosa from other potentially serious conditions to avoid unnecessary treatment.
==See also==
==See also==
*[[Salpingitis isthmica nodosa]]
* [[Vasectomy]]
 
* [[Vas deferens]]
* [[Epididymis]]
==References==
==References==
{{Reflist}}
{{Reflist}}
 
[[Category:Urology]]
== External links ==
[[Category:Benign neoplasms]]
{{Medical resources
[[Category:Reproductive system]]
|  DiseasesDB      = 
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|  ICD10          = 
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}}
[[Category:Contraception for males]]
[[Category:Sterilization]]
[[Category:Male genital disorders]]
 
 
{{genitourinary-disease-stub}}
{{stb}}

Latest revision as of 23:21, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Vasitis nodosa
Vasitis nodosa under intermediate magnification
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Usually asymptomatic, may present as a scrotal mass
Complications Rarely, can be mistaken for vas deferens tumors
Onset
Duration
Types
Causes Surgical procedures such as vasectomy
Risks
Diagnosis Histopathology
Differential diagnosis Sperm granuloma, epididymitis, testicular cancer
Prevention
Treatment Usually none required
Medication
Prognosis Excellent
Frequency Common after vasectomy
Deaths N/A


A benign condition of the vas deferens


Vasitis nodosa is a benign condition affecting the vas deferens, the duct that conveys sperm from the epididymis to the ejaculatory duct. It is characterized by the presence of small nodular lesions along the vas deferens, often resulting from previous vasectomy procedures.

Pathophysiology[edit]

Vasitis nodosa occurs due to the proliferation of epithelial cells and smooth muscle in the vas deferens. This proliferation is typically a response to trauma or surgical intervention, such as a vasectomy. The nodules are composed of hyperplastic tissue, which can sometimes be mistaken for malignant growths, although vasitis nodosa is entirely benign.

Clinical Presentation[edit]

Most individuals with vasitis nodosa are asymptomatic and the condition is often discovered incidentally during histological examination following a vasectomy reversal or other surgical procedures involving the vas deferens. In rare cases, patients may experience discomfort or pain in the scrotal region.

Diagnosis[edit]

Diagnosis of vasitis nodosa is primarily made through histological examination. The nodules are identified by their characteristic appearance under a microscope, showing proliferation of epithelial and smooth muscle cells. Imaging studies are not typically used for diagnosis.

Treatment[edit]

Vasitis nodosa does not usually require treatment, as it is a benign condition. In cases where it causes discomfort or is mistaken for a malignant condition, surgical intervention may be considered. However, this is rare.

Prognosis[edit]

The prognosis for individuals with vasitis nodosa is excellent, as the condition is benign and does not affect fertility or overall health. It is important for healthcare providers to distinguish vasitis nodosa from other potentially serious conditions to avoid unnecessary treatment.

See also[edit]

References[edit]

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