Myoglobinuria: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Myoglobinuria | |||
| image = [[File:RhabdoUrine.JPG|left|thumb|Urine sample showing myoglobinuria]] | |||
| caption = Urine sample showing myoglobinuria | |||
| field = [[Nephrology]] | |||
| symptoms = [[Dark urine]], [[muscle pain]], [[weakness]] | |||
| complications = [[Acute kidney injury]], [[electrolyte imbalance]] | |||
| onset = Sudden | |||
| duration = Varies | |||
| causes = [[Rhabdomyolysis]], [[trauma]], [[seizures]], [[extreme exercise]] | |||
| risks = [[Dehydration]], [[genetic disorders]], [[drug use]] | |||
| diagnosis = [[Urinalysis]], [[blood test]] | |||
| differential = [[Hematuria]], [[bilirubinuria]] | |||
| treatment = [[Intravenous fluids]], [[dialysis]] | |||
| prognosis = Depends on underlying cause and treatment | |||
| frequency = Rare | |||
}} | |||
[[File:Myoglobin.png|Myoglobin|thumb|left]] | |||
'''Myoglobinuria''' is a medical condition characterized by the presence of [[myoglobin]] in the urine, usually associated with muscle destruction. Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of most mammals. When the muscle tissue is damaged, myoglobin is released into the bloodstream and eventually appears in the urine, causing it to turn a dark brown color. | '''Myoglobinuria''' is a medical condition characterized by the presence of [[myoglobin]] in the urine, usually associated with muscle destruction. Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of most mammals. When the muscle tissue is damaged, myoglobin is released into the bloodstream and eventually appears in the urine, causing it to turn a dark brown color. | ||
== Causes == | == Causes == | ||
Myoglobinuria can be caused by any condition that results in muscle damage, including: | Myoglobinuria can be caused by any condition that results in muscle damage, including: | ||
* [[Trauma]] or crush injuries | * [[Trauma]] or crush injuries | ||
* [[Burns]] | * [[Burns]] | ||
| Line 13: | Line 30: | ||
* Prolonged [[coma]] | * Prolonged [[coma]] | ||
* Extreme physical activity, especially in untrained individuals | * Extreme physical activity, especially in untrained individuals | ||
== Symptoms == | == Symptoms == | ||
The primary symptom of myoglobinuria is dark or brown urine. Other symptoms can include muscle weakness or pain, fatigue, and in severe cases, kidney failure. | The primary symptom of myoglobinuria is dark or brown urine. Other symptoms can include muscle weakness or pain, fatigue, and in severe cases, kidney failure. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of myoglobinuria typically involves a urine test to detect the presence of myoglobin. Blood tests may also be used to measure levels of [[creatine kinase]], an enzyme that is released into the bloodstream when muscle tissue is damaged. | Diagnosis of myoglobinuria typically involves a urine test to detect the presence of myoglobin. Blood tests may also be used to measure levels of [[creatine kinase]], an enzyme that is released into the bloodstream when muscle tissue is damaged. | ||
== Treatment == | == Treatment == | ||
Treatment for myoglobinuria primarily involves treating the underlying cause of the muscle damage. This may include rehydration to help flush the myoglobin out of the kidneys, medications to control symptoms, and in severe cases, dialysis to remove the myoglobin from the blood. | Treatment for myoglobinuria primarily involves treating the underlying cause of the muscle damage. This may include rehydration to help flush the myoglobin out of the kidneys, medications to control symptoms, and in severe cases, dialysis to remove the myoglobin from the blood. | ||
== See also == | == See also == | ||
* [[Rhabdomyolysis]] | * [[Rhabdomyolysis]] | ||
* [[Hematuria]] | * [[Hematuria]] | ||
* [[Proteinuria]] | * [[Proteinuria]] | ||
[[Category:Urological conditions]] | [[Category:Urological conditions]] | ||
[[Category:Musculoskeletal disorders]] | [[Category:Musculoskeletal disorders]] | ||
[[Category:Medical terminology]] | [[Category:Medical terminology]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 05:36, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Myoglobinuria | |
|---|---|
 | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Dark urine, muscle pain, weakness |
| Complications | Acute kidney injury, electrolyte imbalance |
| Onset | Sudden |
| Duration | Varies |
| Types | N/A |
| Causes | Rhabdomyolysis, trauma, seizures, extreme exercise |
| Risks | Dehydration, genetic disorders, drug use |
| Diagnosis | Urinalysis, blood test |
| Differential diagnosis | Hematuria, bilirubinuria |
| Prevention | N/A |
| Treatment | Intravenous fluids, dialysis |
| Medication | N/A |
| Prognosis | Depends on underlying cause and treatment |
| Frequency | Rare |
| Deaths | N/A |
Myoglobinuria is a medical condition characterized by the presence of myoglobin in the urine, usually associated with muscle destruction. Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of most mammals. When the muscle tissue is damaged, myoglobin is released into the bloodstream and eventually appears in the urine, causing it to turn a dark brown color.
Causes[edit]
Myoglobinuria can be caused by any condition that results in muscle damage, including:
- Trauma or crush injuries
- Burns
- Seizures
- Metabolic disorders such as McArdle's disease
- Infections that produce muscle inflammation
- Alcohol abuse
- Certain medications and drugs
- Prolonged coma
- Extreme physical activity, especially in untrained individuals
Symptoms[edit]
The primary symptom of myoglobinuria is dark or brown urine. Other symptoms can include muscle weakness or pain, fatigue, and in severe cases, kidney failure.
Diagnosis[edit]
Diagnosis of myoglobinuria typically involves a urine test to detect the presence of myoglobin. Blood tests may also be used to measure levels of creatine kinase, an enzyme that is released into the bloodstream when muscle tissue is damaged.
Treatment[edit]
Treatment for myoglobinuria primarily involves treating the underlying cause of the muscle damage. This may include rehydration to help flush the myoglobin out of the kidneys, medications to control symptoms, and in severe cases, dialysis to remove the myoglobin from the blood.
