Mercury granuloma: Difference between revisions

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'''Mercury granuloma''' is a medical condition that results from the body's reaction to the presence of mercury in the body. This condition is characterized by the formation of granulomas, which are small areas of inflammation, in response to the mercury.
{{SI}}
 
{{Infobox medical condition
Mercury granuloma can occur as a result of exposure to mercury in various forms, including elemental mercury, inorganic mercury compounds, and organic mercury compounds. The most common sources of mercury exposure include dental amalgams, fish and shellfish, certain vaccines, and occupational exposure in industries such as mining and manufacturing.
| name            = Mercury granuloma
 
| image          = [[File:Mercury_-_Skin.jpg|250px]]
The symptoms of mercury granuloma can vary depending on the form of mercury involved and the extent of exposure. Common symptoms include fatigue, depression, anxiety, and cognitive difficulties. In severe cases, mercury granuloma can lead to kidney damage, respiratory failure, and death.
| caption        = Skin affected by mercury granuloma
 
| field          = [[Dermatology]]
The diagnosis of mercury granuloma is typically made based on a combination of the patient's history of mercury exposure, clinical symptoms, and laboratory tests. Treatment involves removing the source of mercury exposure and providing supportive care to manage symptoms.
| symptoms        = [[Skin lesion]], [[inflammation]], [[pain]]
 
| complications  = [[Chronic inflammation]], [[scarring]]
[[Category:Medical conditions]]
| onset          = After exposure to [[mercury]]
[[Category:Toxicology]]
| duration        = Variable, can be chronic
[[Category:Occupational diseases]]
| causes          = [[Mercury]] exposure, often from [[amalgam tattoo]] or [[mercury poisoning]]
 
| risks          = Handling of [[mercury]], [[dental work]]
== Symptoms ==
| diagnosis      = [[Biopsy]], [[histopathology]]
The symptoms of mercury granuloma can vary widely depending on the form of mercury involved and the extent of exposure. Common symptoms include:
| differential    = [[Foreign body granuloma]], [[tattoo granuloma]]
 
| prevention      = Avoidance of [[mercury]] exposure
* Fatigue
| treatment      = [[Surgical excision]], [[corticosteroids]]
* Depression
| prognosis      = Generally good with treatment
* Anxiety
| frequency      = Rare
* Cognitive difficulties
}}
* Kidney damage
A '''mercury granuloma''' is a type of [[granuloma]] that forms in response to the presence of [[mercury]] in the tissues. Granulomas are small areas of inflammation caused by a collection of immune cells known as [[macrophages]]. These cells attempt to wall off substances that they perceive as foreign but are unable to eliminate.
* Respiratory failure
== Pathophysiology ==
 
Mercury granulomas occur when mercury, often from [[amalgam]] dental fillings or other sources, becomes embedded in the skin or other tissues. The body recognizes the mercury as a foreign substance and mounts an immune response. This response involves the aggregation of macrophages and other immune cells, forming a granuloma.
== Causes ==
== Clinical Presentation ==
Mercury granuloma can occur as a result of exposure to mercury in various forms, including:
Patients with mercury granulomas may present with localized skin lesions that are often firm and nodular. These lesions can be painful or itchy and may vary in color from red to purple. The skin overlying the granuloma may become ulcerated in some cases.
 
* Elemental mercury
* Inorganic mercury compounds
* Organic mercury compounds
 
The most common sources of mercury exposure include:
 
* Dental amalgams
* Fish and shellfish
* Certain vaccines
* Occupational exposure in industries such as mining and manufacturing
 
== Diagnosis ==
== Diagnosis ==
The diagnosis of mercury granuloma is typically made based on a combination of the patient's history of mercury exposure, clinical symptoms, and laboratory tests.
The diagnosis of mercury granuloma is typically made based on the clinical appearance of the lesions and the patient's history of exposure to mercury. A [[biopsy]] of the lesion can confirm the diagnosis by revealing the characteristic granulomatous inflammation and the presence of mercury deposits.
 
== Treatment ==
== Treatment ==
Treatment for mercury granuloma involves removing the source of mercury exposure and providing supportive care to manage symptoms.
Treatment of mercury granulomas involves the removal of the source of mercury exposure, if possible. Surgical excision of the granuloma may be necessary in some cases. Topical or systemic [[corticosteroids]] may be used to reduce inflammation and alleviate symptoms.
 
== Prevention ==
Preventing mercury granulomas involves minimizing exposure to mercury. This can include using alternative materials for dental fillings and taking precautions when handling mercury-containing substances.
== See also ==
== See also ==
* [[Granuloma]]
* [[Mercury poisoning]]
* [[Mercury poisoning]]
* [[Heavy metal poisoning]]
* [[Amalgam (dentistry)]]
* [[Occupational disease]]
[[Category:Dermatology]]
 
[[Category:Inflammatory conditions]]
{{stub}}
 
== References ==
<references />
 
== External links ==
* [https://www.who.int/news-room/fact-sheets/detail/mercury-and-health World Health Organization: Mercury and Health]
* [https://www.cdc.gov/niosh/topics/mercury/ CDC: Mercury]
 
[[Category:Medical conditions]]
[[Category:Toxicology]]
[[Category:Occupational diseases]]
{{dictionary-stub1}}

Latest revision as of 03:51, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Mercury granuloma
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Skin lesion, inflammation, pain
Complications Chronic inflammation, scarring
Onset After exposure to mercury
Duration Variable, can be chronic
Types N/A
Causes Mercury exposure, often from amalgam tattoo or mercury poisoning
Risks Handling of mercury, dental work
Diagnosis Biopsy, histopathology
Differential diagnosis Foreign body granuloma, tattoo granuloma
Prevention Avoidance of mercury exposure
Treatment Surgical excision, corticosteroids
Medication N/A
Prognosis Generally good with treatment
Frequency Rare
Deaths N/A


A mercury granuloma is a type of granuloma that forms in response to the presence of mercury in the tissues. Granulomas are small areas of inflammation caused by a collection of immune cells known as macrophages. These cells attempt to wall off substances that they perceive as foreign but are unable to eliminate.

Pathophysiology[edit]

Mercury granulomas occur when mercury, often from amalgam dental fillings or other sources, becomes embedded in the skin or other tissues. The body recognizes the mercury as a foreign substance and mounts an immune response. This response involves the aggregation of macrophages and other immune cells, forming a granuloma.

Clinical Presentation[edit]

Patients with mercury granulomas may present with localized skin lesions that are often firm and nodular. These lesions can be painful or itchy and may vary in color from red to purple. The skin overlying the granuloma may become ulcerated in some cases.

Diagnosis[edit]

The diagnosis of mercury granuloma is typically made based on the clinical appearance of the lesions and the patient's history of exposure to mercury. A biopsy of the lesion can confirm the diagnosis by revealing the characteristic granulomatous inflammation and the presence of mercury deposits.

Treatment[edit]

Treatment of mercury granulomas involves the removal of the source of mercury exposure, if possible. Surgical excision of the granuloma may be necessary in some cases. Topical or systemic corticosteroids may be used to reduce inflammation and alleviate symptoms.

Prevention[edit]

Preventing mercury granulomas involves minimizing exposure to mercury. This can include using alternative materials for dental fillings and taking precautions when handling mercury-containing substances.

See also[edit]