Lymphoproliferative disorders: Difference between revisions
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{{Infobox medical condition | |||
| name = Lymphoproliferative disorders | |||
| image = [[File:Diffuse_large_B_cell_lymphoma_(1)_tonsil.jpg|250px]] | |||
| caption = Micrograph of diffuse large B-cell lymphoma, a type of lymphoproliferative disorder | |||
| field = [[Hematology]] | |||
| symptoms = [[Lymphadenopathy]], [[fever]], [[night sweats]], [[weight loss]] | |||
| complications = [[Infection]], [[anemia]], [[organ failure]] | |||
| onset = Variable, often in [[adulthood]] | |||
| duration = Chronic | |||
| types = [[Non-Hodgkin lymphoma]], [[Hodgkin lymphoma]], [[Chronic lymphocytic leukemia]], [[Multiple myeloma]] | |||
| causes = [[Genetic mutations]], [[viral infections]] (e.g., [[Epstein-Barr virus]]) | |||
| risks = [[Immunosuppression]], [[autoimmune diseases]], [[family history]] | |||
| diagnosis = [[Blood tests]], [[bone marrow biopsy]], [[imaging studies]] | |||
| treatment = [[Chemotherapy]], [[radiation therapy]], [[immunotherapy]], [[stem cell transplant]] | |||
| prognosis = Variable, depends on type and stage | |||
| frequency = Common | |||
}} | |||
'''Lymphoproliferative disorders''' are diseases characterized by the abnormal proliferation of lymphocytes, a type of white blood cell. These disorders can be benign or malignant and can affect both children and adults. They are often associated with immune system dysfunction. | '''Lymphoproliferative disorders''' are diseases characterized by the abnormal proliferation of lymphocytes, a type of white blood cell. These disorders can be benign or malignant and can affect both children and adults. They are often associated with immune system dysfunction. | ||
==Types of Lymphoproliferative Disorders== | ==Types of Lymphoproliferative Disorders== | ||
There are several types of lymphoproliferative disorders, including: | There are several types of lymphoproliferative disorders, including: | ||
* [[Chronic lymphocytic leukemia]] (CLL) | * [[Chronic lymphocytic leukemia]] (CLL) | ||
* [[Non-Hodgkin lymphoma]] (NHL) | * [[Non-Hodgkin lymphoma]] (NHL) | ||
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* [[Multiple myeloma]] (MM) | * [[Multiple myeloma]] (MM) | ||
* [[Waldenström macroglobulinemia]] (WM) | * [[Waldenström macroglobulinemia]] (WM) | ||
==Causes== | ==Causes== | ||
The exact cause of lymphoproliferative disorders is unknown, but they are often associated with immune system dysfunction. Some disorders are linked to specific genetic mutations, while others may be triggered by infections or exposure to certain chemicals or radiation. | The exact cause of lymphoproliferative disorders is unknown, but they are often associated with immune system dysfunction. Some disorders are linked to specific genetic mutations, while others may be triggered by infections or exposure to certain chemicals or radiation. | ||
==Symptoms== | ==Symptoms== | ||
Symptoms of lymphoproliferative disorders can vary widely depending on the specific disorder and the individual patient. Common symptoms may include: | Symptoms of lymphoproliferative disorders can vary widely depending on the specific disorder and the individual patient. Common symptoms may include: | ||
* Fatigue | * Fatigue | ||
* Fever | * Fever | ||
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* Weight loss | * Weight loss | ||
* Swollen lymph nodes | * Swollen lymph nodes | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of lymphoproliferative disorders typically involves a combination of physical examination, medical history, laboratory tests, and imaging studies. A biopsy of affected tissue may also be performed. | Diagnosis of lymphoproliferative disorders typically involves a combination of physical examination, medical history, laboratory tests, and imaging studies. A biopsy of affected tissue may also be performed. | ||
==Treatment== | ==Treatment== | ||
Treatment for lymphoproliferative disorders depends on the specific disorder and the patient's overall health. Options may include chemotherapy, radiation therapy, immunotherapy, targeted therapy, stem cell transplant, or a combination of these. | Treatment for lymphoproliferative disorders depends on the specific disorder and the patient's overall health. Options may include chemotherapy, radiation therapy, immunotherapy, targeted therapy, stem cell transplant, or a combination of these. | ||
==See Also== | ==See Also== | ||
* [[Leukemia]] | * [[Leukemia]] | ||
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* [[Myeloma]] | * [[Myeloma]] | ||
* [[Waldenström macroglobulinemia]] | * [[Waldenström macroglobulinemia]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 02:38, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Lymphoproliferative disorders | |
|---|---|
_tonsil.jpg)
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Lymphadenopathy, fever, night sweats, weight loss |
| Complications | Infection, anemia, organ failure |
| Onset | Variable, often in adulthood |
| Duration | Chronic |
| Types | Non-Hodgkin lymphoma, Hodgkin lymphoma, Chronic lymphocytic leukemia, Multiple myeloma |
| Causes | Genetic mutations, viral infections (e.g., Epstein-Barr virus) |
| Risks | Immunosuppression, autoimmune diseases, family history |
| Diagnosis | Blood tests, bone marrow biopsy, imaging studies |
| Differential diagnosis | N/A |
| Prevention | N/A |
| Treatment | Chemotherapy, radiation therapy, immunotherapy, stem cell transplant |
| Medication | N/A |
| Prognosis | Variable, depends on type and stage |
| Frequency | Common |
| Deaths | N/A |
Lymphoproliferative disorders are diseases characterized by the abnormal proliferation of lymphocytes, a type of white blood cell. These disorders can be benign or malignant and can affect both children and adults. They are often associated with immune system dysfunction.
Types of Lymphoproliferative Disorders[edit]
There are several types of lymphoproliferative disorders, including:
- Chronic lymphocytic leukemia (CLL)
- Non-Hodgkin lymphoma (NHL)
- Hodgkin lymphoma (HL)
- Multiple myeloma (MM)
- Waldenström macroglobulinemia (WM)
Causes[edit]
The exact cause of lymphoproliferative disorders is unknown, but they are often associated with immune system dysfunction. Some disorders are linked to specific genetic mutations, while others may be triggered by infections or exposure to certain chemicals or radiation.
Symptoms[edit]
Symptoms of lymphoproliferative disorders can vary widely depending on the specific disorder and the individual patient. Common symptoms may include:
- Fatigue
- Fever
- Night sweats
- Weight loss
- Swollen lymph nodes
Diagnosis[edit]
Diagnosis of lymphoproliferative disorders typically involves a combination of physical examination, medical history, laboratory tests, and imaging studies. A biopsy of affected tissue may also be performed.
Treatment[edit]
Treatment for lymphoproliferative disorders depends on the specific disorder and the patient's overall health. Options may include chemotherapy, radiation therapy, immunotherapy, targeted therapy, stem cell transplant, or a combination of these.
