Late-onset hypogonadism: Difference between revisions
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{{Infobox medical condition | |||
| name = Late-onset hypogonadism | |||
| synonyms = Andropause, Testosterone deficiency syndrome | |||
| field = [[Endocrinology]] | |||
| symptoms = [[Fatigue (medical)|Fatigue]], [[depression (mood)|depression]], [[erectile dysfunction]], [[decreased libido]], [[muscle weakness]], [[osteoporosis]] | |||
| complications = [[Cardiovascular disease]], [[osteoporosis]], [[metabolic syndrome]] | |||
| onset = Typically after age 40 | |||
| duration = Chronic | |||
| causes = [[Aging]], [[obesity]], [[chronic illness]] | |||
| risks = [[Obesity]], [[diabetes]], [[hypertension]], [[smoking]] | |||
| diagnosis = [[Blood test]] for [[testosterone]] levels, clinical evaluation | |||
| differential = [[Primary hypogonadism]], [[depression]], [[thyroid disorders]] | |||
| treatment = [[Testosterone replacement therapy]], lifestyle changes | |||
| medication = [[Testosterone]] gels, patches, injections | |||
| frequency = Common in older men | |||
| deaths = Rarely directly fatal | |||
}} | |||
'''Late-onset hypogonadism''' is a medical condition in men characterized by the decline in [[testosterone]] production with aging. It is also known as '''andropause''' or '''male menopause'''. | '''Late-onset hypogonadism''' is a medical condition in men characterized by the decline in [[testosterone]] production with aging. It is also known as '''andropause''' or '''male menopause'''. | ||
==Definition== | ==Definition== | ||
[[Late-onset hypogonadism]] is defined as a syndrome in men associated with advancing age, characterized by particular symptoms and a deficiency in serum testosterone levels. The [[European Male Aging Study]] has defined late-onset hypogonadism as a biochemical syndrome associated with aging and characterized by a deficiency in serum testosterone levels below the young healthy adult male reference range. | [[Late-onset hypogonadism]] is defined as a syndrome in men associated with advancing age, characterized by particular symptoms and a deficiency in serum testosterone levels. The [[European Male Aging Study]] has defined late-onset hypogonadism as a biochemical syndrome associated with aging and characterized by a deficiency in serum testosterone levels below the young healthy adult male reference range. | ||
==Symptoms== | ==Symptoms== | ||
Symptoms of late-onset hypogonadism include decreased [[libido]], erectile dysfunction, reduced muscle mass and strength, increased body fat, decreased bone mineral density, and anemia. Other symptoms may include reduced vitality, depressed mood, and cognitive decline. | Symptoms of late-onset hypogonadism include decreased [[libido]], erectile dysfunction, reduced muscle mass and strength, increased body fat, decreased bone mineral density, and anemia. Other symptoms may include reduced vitality, depressed mood, and cognitive decline. | ||
==Causes== | ==Causes== | ||
The primary cause of late-onset hypogonadism is aging. Other factors that may contribute to the development of this condition include obesity, metabolic syndrome, and type 2 diabetes. | The primary cause of late-onset hypogonadism is aging. Other factors that may contribute to the development of this condition include obesity, metabolic syndrome, and type 2 diabetes. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of late-onset hypogonadism involves the measurement of serum testosterone levels. The [[Endocrine Society]] recommends making a diagnosis of late-onset hypogonadism only in men with consistent symptoms and signs and unequivocally low serum testosterone levels. | Diagnosis of late-onset hypogonadism involves the measurement of serum testosterone levels. The [[Endocrine Society]] recommends making a diagnosis of late-onset hypogonadism only in men with consistent symptoms and signs and unequivocally low serum testosterone levels. | ||
==Treatment== | ==Treatment== | ||
Treatment for late-onset hypogonadism is typically with testosterone replacement therapy. This therapy can help to alleviate symptoms and improve quality of life. However, it is not without risks and potential side effects, and should be considered carefully in consultation with a healthcare provider. | Treatment for late-onset hypogonadism is typically with testosterone replacement therapy. This therapy can help to alleviate symptoms and improve quality of life. However, it is not without risks and potential side effects, and should be considered carefully in consultation with a healthcare provider. | ||
==See also== | ==See also== | ||
* [[Testosterone]] | * [[Testosterone]] | ||
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* [[Endocrine Society]] | * [[Endocrine Society]] | ||
* [[European Male Aging Study]] | * [[European Male Aging Study]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Men's health]] | [[Category:Men's health]] | ||
[[Category:Geriatrics]] | [[Category:Geriatrics]] | ||
[[Category:Andrology]] | [[Category:Andrology]] | ||
{{Endocrinology-stub}} | {{Endocrinology-stub}} | ||
{{Men's-health-stub}} | {{Men's-health-stub}} | ||
Latest revision as of 06:13, 4 April 2025
| Late-onset hypogonadism | |
|---|---|
| Synonyms | Andropause, Testosterone deficiency syndrome |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fatigue, depression, erectile dysfunction, decreased libido, muscle weakness, osteoporosis |
| Complications | Cardiovascular disease, osteoporosis, metabolic syndrome |
| Onset | Typically after age 40 |
| Duration | Chronic |
| Types | N/A |
| Causes | Aging, obesity, chronic illness |
| Risks | Obesity, diabetes, hypertension, smoking |
| Diagnosis | Blood test for testosterone levels, clinical evaluation |
| Differential diagnosis | Primary hypogonadism, depression, thyroid disorders |
| Prevention | N/A |
| Treatment | Testosterone replacement therapy, lifestyle changes |
| Medication | Testosterone gels, patches, injections |
| Prognosis | N/A |
| Frequency | Common in older men |
| Deaths | Rarely directly fatal |
Late-onset hypogonadism is a medical condition in men characterized by the decline in testosterone production with aging. It is also known as andropause or male menopause.
Definition[edit]
Late-onset hypogonadism is defined as a syndrome in men associated with advancing age, characterized by particular symptoms and a deficiency in serum testosterone levels. The European Male Aging Study has defined late-onset hypogonadism as a biochemical syndrome associated with aging and characterized by a deficiency in serum testosterone levels below the young healthy adult male reference range.
Symptoms[edit]
Symptoms of late-onset hypogonadism include decreased libido, erectile dysfunction, reduced muscle mass and strength, increased body fat, decreased bone mineral density, and anemia. Other symptoms may include reduced vitality, depressed mood, and cognitive decline.
Causes[edit]
The primary cause of late-onset hypogonadism is aging. Other factors that may contribute to the development of this condition include obesity, metabolic syndrome, and type 2 diabetes.
Diagnosis[edit]
Diagnosis of late-onset hypogonadism involves the measurement of serum testosterone levels. The Endocrine Society recommends making a diagnosis of late-onset hypogonadism only in men with consistent symptoms and signs and unequivocally low serum testosterone levels.
Treatment[edit]
Treatment for late-onset hypogonadism is typically with testosterone replacement therapy. This therapy can help to alleviate symptoms and improve quality of life. However, it is not without risks and potential side effects, and should be considered carefully in consultation with a healthcare provider.
See also[edit]

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