Keratoglobus: Difference between revisions
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{{Infobox medical condition | |||
| name = Keratoglobus | |||
| synonyms = | |||
| pronunciation = | |||
| image = | |||
| caption = | |||
| field = [[Ophthalmology]] | |||
| symptoms = [[Thinning of the cornea]], [[corneal ectasia]], [[vision impairment]] | |||
| complications = [[Corneal rupture]], [[vision loss]] | |||
| onset = Usually present at birth or develops in early childhood | |||
| duration = Chronic | |||
| types = | |||
| causes = [[Genetic factors]], [[connective tissue disorders]] | |||
| risks = | |||
| diagnosis = [[Slit-lamp examination]], [[corneal topography]] | |||
| differential = [[Keratoconus]], [[pellucid marginal degeneration]] | |||
| prevention = | |||
| treatment = [[Contact lenses]], [[corneal transplantation]] | |||
| medication = | |||
| prognosis = Variable, depending on severity and treatment | |||
| frequency = Rare | |||
}} | |||
'''Keratoglobus''' is a rare, non-inflammatory, bilateral [[eye disorder]] that results in a generalized thinning and globular protrusion of the [[cornea]]. This condition is typically present at birth and is characterized by a round, symmetrically enlarged cornea. | '''Keratoglobus''' is a rare, non-inflammatory, bilateral [[eye disorder]] that results in a generalized thinning and globular protrusion of the [[cornea]]. This condition is typically present at birth and is characterized by a round, symmetrically enlarged cornea. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of Keratoglobus can vary, but often include: | The symptoms of Keratoglobus can vary, but often include: | ||
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* [[Astigmatism]] | * [[Astigmatism]] | ||
* [[Myopia]] (nearsightedness) | * [[Myopia]] (nearsightedness) | ||
== Causes == | == Causes == | ||
The exact cause of Keratoglobus is unknown, but it is believed to be associated with conditions such as: | The exact cause of Keratoglobus is unknown, but it is believed to be associated with conditions such as: | ||
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* [[Blue sclera syndrome]] | * [[Blue sclera syndrome]] | ||
* [[Marfan syndrome]] | * [[Marfan syndrome]] | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of Keratoglobus is typically made through a comprehensive [[eye examination]]. This may include: | Diagnosis of Keratoglobus is typically made through a comprehensive [[eye examination]]. This may include: | ||
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* [[Corneal topography]] | * [[Corneal topography]] | ||
* [[Optical coherence tomography]] | * [[Optical coherence tomography]] | ||
== Treatment == | == Treatment == | ||
Treatment options for Keratoglobus are limited and often challenging due to the thin and fragile nature of the cornea. They may include: | Treatment options for Keratoglobus are limited and often challenging due to the thin and fragile nature of the cornea. They may include: | ||
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* [[Corneal transplant]] | * [[Corneal transplant]] | ||
* [[Keratoprosthesis]] | * [[Keratoprosthesis]] | ||
== See also == | == See also == | ||
* [[Corneal ectasia]] | * [[Corneal ectasia]] | ||
* [[Keratoconus]] | * [[Keratoconus]] | ||
* [[Pellucid marginal degeneration]] | * [[Pellucid marginal degeneration]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
== External links == | == External links == | ||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775061/ Keratoglobus] at [[National Center for Biotechnology Information]] | * [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775061/ Keratoglobus] at [[National Center for Biotechnology Information]] | ||
* [https://rarediseases.info.nih.gov/diseases/1078/keratoglobus Keratoglobus] at [[National Organization for Rare Disorders]] | * [https://rarediseases.info.nih.gov/diseases/1078/keratoglobus Keratoglobus] at [[National Organization for Rare Disorders]] | ||
[[Category:Eye diseases]] | [[Category:Eye diseases]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
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{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 04:14, 4 April 2025
| Keratoglobus | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Thinning of the cornea, corneal ectasia, vision impairment |
| Complications | Corneal rupture, vision loss |
| Onset | Usually present at birth or develops in early childhood |
| Duration | Chronic |
| Types | |
| Causes | Genetic factors, connective tissue disorders |
| Risks | |
| Diagnosis | Slit-lamp examination, corneal topography |
| Differential diagnosis | Keratoconus, pellucid marginal degeneration |
| Prevention | |
| Treatment | Contact lenses, corneal transplantation |
| Medication | |
| Prognosis | Variable, depending on severity and treatment |
| Frequency | Rare |
| Deaths | N/A |
Keratoglobus is a rare, non-inflammatory, bilateral eye disorder that results in a generalized thinning and globular protrusion of the cornea. This condition is typically present at birth and is characterized by a round, symmetrically enlarged cornea.
Symptoms[edit]
The symptoms of Keratoglobus can vary, but often include:
- Visual impairment
- Photophobia (sensitivity to light)
- Astigmatism
- Myopia (nearsightedness)
Causes[edit]
The exact cause of Keratoglobus is unknown, but it is believed to be associated with conditions such as:
Diagnosis[edit]
Diagnosis of Keratoglobus is typically made through a comprehensive eye examination. This may include:
Treatment[edit]
Treatment options for Keratoglobus are limited and often challenging due to the thin and fragile nature of the cornea. They may include:
See also[edit]
References[edit]
<references />
