Dimethyltrienolone: Difference between revisions

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'''Dimethyltrienolone''' is a [[synthetic]] [[androgen]] and [[anabolic steroid]] (AAS) and a [[17α-alkylated]] [[nandrolone]] (19-nortestosterone) derivative which was never marketed. It is one of the most potent AAS to have ever been synthesized, with reportedly the highest ratio of [[anabolic]] to [[androgenic]] activity of any AAS.
{{DISPLAYTITLE:Dimethyltrienolone}}


==Chemistry==
== Dimethyltrienolone ==
Dimethyltrienolone, also known as 7α,17α-dimethyl-19-nortestosterone or as 7α,17α-dimethylestr-4-en-17β-ol-3-one, is a [[synthetic]] [[estrane]] steroid and a [[17α-alkylated]] derivative of [[nandrolone]].


==Pharmacology==
[[File:Dimethyltrienolone.svg|thumb|right|Chemical structure of Dimethyltrienolone]]
As an [[AAS]], dimethyltrienolone is an [[agonist]] of the [[androgen receptor]] (AR), the biological target of androgens like [[testosterone]] and [[dihydrotestosterone]] (DHT). It has strong anabolic effects and weak androgenic effects, which give it a mild side effect profile and make it especially suitable for use in women.


==Side effects==
'''Dimethyltrienolone''' is a potent [[anabolic steroid]] that is derived from [[nandrolone]]. It is known for its high [[androgen receptor]] binding affinity and significant anabolic effects. Dimethyltrienolone is a synthetic [[androgen]] and [[anabolic steroid]] (AAS) that has been studied for its potential use in [[medicine]] and [[sports]].
Potential side effects of dimethyltrienolone include [[virilization]] and [[hepatotoxicity]] among others. As with all AAS, it can also have negative effects on [[cardiovascular health]], including [[lipid profile]] changes and [[hypertension]].


==History==
== Chemical Properties ==
Dimethyltrienolone was first described in the literature in 1967. It was found to have the highest ratio of anabolic to androgenic effects of any steroid yet discovered, but was never marketed due to concerns about its potential for side effects.


==See also==
Dimethyltrienolone is chemically related to [[trenbolone]], another powerful anabolic steroid. It is characterized by the addition of two methyl groups at the 17_ position, which enhances its oral bioavailability and resistance to [[metabolism]]. The chemical structure of Dimethyltrienolone is depicted in the adjacent image.
* [[List of androgens/anabolic steroids]]
* [[List of androgen esters]]
* [[List of steroid abbreviations]]


[[Category:Androgens and anabolic steroids]]
== Mechanism of Action ==
[[Category:Estranes]]
 
[[Category:Ketones]]
Dimethyltrienolone exerts its effects by binding to the androgen receptor, which leads to the activation of [[gene transcription]] and subsequent protein synthesis. This results in increased muscle mass and strength. The compound is known for its strong anabolic effects, which are significantly greater than those of [[testosterone]].
[[Category:Progestogens]]
 
{{pharm-stub}}
== Medical and Non-Medical Use ==
{{medicine-stub}}
 
While Dimethyltrienolone has been studied for potential therapeutic applications, such as in the treatment of [[muscle wasting]] and [[osteoporosis]], it has not been approved for medical use due to its high potential for [[hepatotoxicity]] and other adverse effects. In the realm of [[sports]], it is considered a [[performance-enhancing drug]] and is banned by most sporting organizations.
 
== Side Effects ==
 
The use of Dimethyltrienolone is associated with several side effects, primarily due to its potent androgenic activity. These include:
 
* [[Liver damage]]
* [[Hypertension]]
* [[Acne]]
* [[Hair loss]]
* [[Virilization]] in females
 
Due to these risks, its use is generally discouraged outside of controlled research settings.
 
== Related Compounds ==
 
Dimethyltrienolone is related to other anabolic steroids such as [[trenbolone]], [[nandrolone]], and [[methandrostenolone]]. These compounds share similar mechanisms of action but differ in their potency and side effect profiles.
 
== Related Pages ==
 
* [[Anabolic steroid]]
* [[Androgen receptor]]
* [[Performance-enhancing drugs]]
* [[Trenbolone]]
 
[[Category:Anabolic steroids]]
[[Category:Androgens]]
[[Category:Performance-enhancing drugs]]

Latest revision as of 11:11, 15 February 2025


Dimethyltrienolone[edit]

Chemical structure of Dimethyltrienolone

Dimethyltrienolone is a potent anabolic steroid that is derived from nandrolone. It is known for its high androgen receptor binding affinity and significant anabolic effects. Dimethyltrienolone is a synthetic androgen and anabolic steroid (AAS) that has been studied for its potential use in medicine and sports.

Chemical Properties[edit]

Dimethyltrienolone is chemically related to trenbolone, another powerful anabolic steroid. It is characterized by the addition of two methyl groups at the 17_ position, which enhances its oral bioavailability and resistance to metabolism. The chemical structure of Dimethyltrienolone is depicted in the adjacent image.

Mechanism of Action[edit]

Dimethyltrienolone exerts its effects by binding to the androgen receptor, which leads to the activation of gene transcription and subsequent protein synthesis. This results in increased muscle mass and strength. The compound is known for its strong anabolic effects, which are significantly greater than those of testosterone.

Medical and Non-Medical Use[edit]

While Dimethyltrienolone has been studied for potential therapeutic applications, such as in the treatment of muscle wasting and osteoporosis, it has not been approved for medical use due to its high potential for hepatotoxicity and other adverse effects. In the realm of sports, it is considered a performance-enhancing drug and is banned by most sporting organizations.

Side Effects[edit]

The use of Dimethyltrienolone is associated with several side effects, primarily due to its potent androgenic activity. These include:

Due to these risks, its use is generally discouraged outside of controlled research settings.

Related Compounds[edit]

Dimethyltrienolone is related to other anabolic steroids such as trenbolone, nandrolone, and methandrostenolone. These compounds share similar mechanisms of action but differ in their potency and side effect profiles.

Related Pages[edit]