Alistipes shahii

Alistipes shahii is a species of bacteria within the genus Alistipes, which is part of the family Rikenellaceae. This bacterium is of particular interest in the field of microbiology and gastroenterology due to its presence in the human gut microbiota.

Taxonomy

Alistipes shahii was first described by Rautio et al. in 2003. It belongs to the phylum Bacteroidota, which is known for its role in the digestion of complex molecules in the gastrointestinal tract. The genus Alistipes includes several species that are commonly found in the intestinal microbiome of humans and other animals.

Morphology and Physiology

Alistipes shahii is a Gram-negative bacterium, characterized by its rod-shaped morphology. It is an anaerobic organism, meaning it does not require oxygen for growth and can thrive in environments where oxygen is absent. The bacterium is non-motile and does not form spores.

Genomic Characteristics

The genome of Alistipes shahii has been sequenced, revealing insights into its metabolic capabilities and potential roles in the gut microbiome. The genome encodes for various enzymes involved in the breakdown of complex carbohydrates, proteins, and lipids, which are crucial for the fermentation processes in the gut.

Ecological Role

Alistipes shahii is a commensal organism in the human gut, contributing to the homeostasis of the intestinal environment. It participates in the fermentation of dietary fibers, producing short-chain fatty acids (SCFAs) such as butyrate, propionate, and acetate, which are important for colon health and energy metabolism.

Clinical Significance

The presence and abundance of Alistipes shahii in the gut microbiota have been associated with various health conditions. Alterations in its population may be linked to inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and other gastrointestinal disorders. Research is ongoing to understand its role in immune modulation and metabolic health.

Research and Applications

Studies on Alistipes shahii are focused on its potential as a probiotic and its role in disease prevention. Understanding its interactions with other microbial species and the host can provide insights into microbiome therapy and personalized medicine.

Conclusion

Alistipes shahii is a significant component of the human gut microbiota, with implications for health and disease. Ongoing research aims to elucidate its functions and potential therapeutic applications.

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