Estradiol/estrone/estriol: Difference between revisions

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'''Estradiol''', '''estrone''', and '''estriol''' are three forms of the female sex hormone [[estrogen]]. They are steroid hormones that play critical roles in the [[reproductive system]], including the menstrual cycle, pregnancy, and secondary sexual characteristics.


==Estradiol==
{{Short description|Overview of Estradiol, Estrone, and Estriol}}
[[File:Estradiol.svg|thumb|Chemical structure of estradiol]]
{{Infobox hormone
'''Estradiol''' (E2) is the most potent and prevalent form of estrogen in the body. It is primarily produced in the [[ovaries]] and, to a lesser extent, in the [[adrenal glands]] and [[fat tissue]]. Estradiol is responsible for the development and maintenance of female secondary sexual characteristics, such as breast development and the distribution of body fat. It also plays a crucial role in the menstrual cycle by promoting the growth and development of the [[uterine lining]].
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==Estrone==
'''Estradiol''', '''Estrone''', and '''Estriol''' are the three main types of [[estrogen]] hormones found in the human body. These hormones play crucial roles in the development and regulation of the [[female reproductive system]] and secondary sexual characteristics.
[[File:Estrone.svg|thumb|Chemical structure of estrone]]
'''Estrone''' (E1) is a weaker form of estrogen that is primarily produced in the ovaries and adrenal glands. It is also produced in fat tissue, especially in postmenopausal women. Estrone is converted into estradiol in the body, but it can also act on its own to influence the development of female secondary sexual characteristics and the menstrual cycle.


==Estriol==
== Estradiol ==
[[File:Estriol.svg|thumb|Chemical structure of estriol]]
[[Estradiol]] (E2) is the most potent and prevalent form of estrogen in [[premenopausal women]]. It is primarily produced by the [[ovaries]], but also in smaller amounts by the [[adrenal glands]] and [[placenta]]. Estradiol is essential for the regulation of the [[menstrual cycle]] and is involved in the development of [[breast tissue]], [[uterine lining]], and [[bone density]].
'''Estriol''' (E3) is the weakest form of estrogen and is primarily produced in the [[placenta]] during pregnancy. It is responsible for promoting the growth and development of the uterus and breasts during pregnancy. Estriol levels increase significantly during pregnancy and drop rapidly after childbirth.


==Health implications==
=== Functions ===
Imbalances in the levels of these hormones can lead to various health problems, including [[menopausal symptoms]], [[osteoporosis]], [[cardiovascular disease]], and certain types of [[cancer]]. Hormone replacement therapy, which often includes estradiol, is commonly used to treat menopausal symptoms. However, this treatment can also increase the risk of certain health problems, such as blood clots and certain types of cancer.
Estradiol is involved in:
* Regulation of the menstrual cycle
* Development of female secondary sexual characteristics
* Maintenance of [[bone health]]
* Modulation of [[mood]] and [[cognitive function]]


==See also==
== Estrone ==
* [[Estrogen]]
[[Estrone]] (E1) is a weaker form of estrogen and is the primary estrogen present in [[postmenopausal women]]. It is produced mainly in the [[adipose tissue]] and [[liver]]. Estrone can be converted into estradiol and vice versa, depending on the body's needs.
 
=== Functions ===
Estrone plays a role in:
* Maintaining [[bone density]]
* Supporting [[cardiovascular health]]
* Modulating [[metabolism]]
 
== Estriol ==
[[Estriol]] (E3) is the weakest of the three estrogens and is primarily produced during [[pregnancy]] by the [[placenta]]. It is considered a marker of fetal health and well-being.
 
=== Functions ===
Estriol is involved in:
* Supporting the growth and development of the [[fetus]]
* Preparing the body for [[labor]] and [[delivery]]
* Modulating the [[immune system]] during pregnancy
 
== Clinical Significance ==
The balance of estradiol, estrone, and estriol is crucial for [[female health]]. Imbalances can lead to conditions such as [[estrogen dominance]], [[osteoporosis]], and [[menstrual disorders]].
 
== See also ==
* [[Estrogen replacement therapy]]
* [[Hormone replacement therapy]]
* [[Hormone replacement therapy]]
* [[Menopause]]
* [[Menopause]]
* [[Osteoporosis]]
* [[Endocrinology]]
* [[Cardiovascular disease]]
 
* [[Cancer]]
== References ==
{{Reflist}}
 
== External links ==
* [https://www.wikimd.com/wiki/Estradiol/estrone/estriol Estradiol, Estrone, Estriol on WikiMD]


[[Category:Estrogens]]
[[Category:Hormones]]
[[Category:Endocrinology]]
[[Category:Endocrinology]]
[[Category:Gynecology]]
[[Category:Women's health]]
[[Category:Pharmacology]]
[[Category:Biochemistry]]
 
{{medicine-stub}}

Latest revision as of 21:16, 27 December 2024


Overview of Estradiol, Estrone, and Estriol



Estradiol, Estrone, Estriol




{{This hormone-related article is a stub.}}


Estradiol, Estrone, and Estriol are the three main types of estrogen hormones found in the human body. These hormones play crucial roles in the development and regulation of the female reproductive system and secondary sexual characteristics.

Estradiol[edit]

Estradiol (E2) is the most potent and prevalent form of estrogen in premenopausal women. It is primarily produced by the ovaries, but also in smaller amounts by the adrenal glands and placenta. Estradiol is essential for the regulation of the menstrual cycle and is involved in the development of breast tissue, uterine lining, and bone density.

Functions[edit]

Estradiol is involved in:

Estrone[edit]

Estrone (E1) is a weaker form of estrogen and is the primary estrogen present in postmenopausal women. It is produced mainly in the adipose tissue and liver. Estrone can be converted into estradiol and vice versa, depending on the body's needs.

Functions[edit]

Estrone plays a role in:

Estriol[edit]

Estriol (E3) is the weakest of the three estrogens and is primarily produced during pregnancy by the placenta. It is considered a marker of fetal health and well-being.

Functions[edit]

Estriol is involved in:

Clinical Significance[edit]

The balance of estradiol, estrone, and estriol is crucial for female health. Imbalances can lead to conditions such as estrogen dominance, osteoporosis, and menstrual disorders.

See also[edit]

References[edit]

<references group="" responsive="1"></references>


External links[edit]

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