Atracurium besilate

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Atracurium Besilate

Atracurium Besilate (pronounced as a-tra-KYOO-ree-um BE-si-late) is a non-depolarizing neuromuscular-blocking agent used primarily in the practice of anesthesia to induce muscle relaxation during surgery or mechanical ventilation.

Etymology

The term 'Atracurium' is derived from its chemical structure, which is a bisquaternary ammonium compound. 'Besilate' refers to the besylate salt form of the drug, which is used for its stability and solubility.

Pharmacology

Atracurium Besilate works by blocking the action of acetylcholine, a neurotransmitter that transmits signals in the nervous system. By inhibiting the action of acetylcholine, Atracurium Besilate prevents nerve impulses from reaching the muscles, thereby causing muscle relaxation.

Clinical Use

Atracurium Besilate is used in a clinical setting to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is also used in intensive care units to manage patients requiring mechanical ventilation for longer periods.

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