Yuremamine
Yuremamine is a phytoindole, a type of alkaloid that was first isolated from the bark of Mimosa tenuiflora in 2005. It is unique among natural indoles due to its complex structure, which includes a novel polycyclic framework. The compound has been found to exhibit psychoactive properties.
History
Yuremamine was first isolated and identified in 2005 by a team of researchers led by Vepsäläinen, J. J., Auriola, S., Tukiainen, M., Ropponen, N., and Callaway, J. C. The team used a combination of liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance (NMR) to determine the structure of the compound.
Structure and Properties
Yuremamine is a purple solid that is soluble in organic solvents. Its structure is unique among natural indoles, consisting of a polycyclic framework that includes a pyrroloindole core and a methoxyindole moiety. The compound also contains a rare spiro-fused tetrahydrofuran ring.
Biological Activity
Yuremamine has been found to exhibit psychoactive properties. It is believed to act as a monoamine oxidase inhibitor (MAOI), which means it can increase the levels of certain chemicals in the brain. This can lead to changes in mood, behavior, and perception. However, the exact mechanisms of action and potential therapeutic uses of yuremamine are still under investigation.
See Also
References
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Contributors: Prab R. Tumpati, MD