Yatapoxvirus
Yatapoxvirus is a genus of viruses in the family Poxviridae and subfamily Chordopoxvirinae. The genus includes two species: Tanapox virus and Yaba monkey tumor virus. These viruses are known to infect humans and non-human primates.
Taxonomy
Yatapoxvirus is a genus in the family Poxviridae, which is a family of large, complex DNA viruses. The family Poxviridae is divided into two subfamilies: Chordopoxvirinae, which infect vertebrates, and Entomopoxvirinae, which infect insects. The genus Yatapoxvirus falls under the subfamily Chordopoxvirinae.
Structure
Like all poxviruses, Yatapoxviruses are large, brick-shaped viruses with a complex structure. The virus particle is surrounded by a lipid membrane and contains a large, linear double-stranded DNA genome.
Life Cycle
The life cycle of Yatapoxviruses, like other poxviruses, involves several stages. The virus first attaches to the host cell and enters the cell. Once inside, the virus uncoats and releases its DNA into the cell's cytoplasm. The viral DNA is then transcribed and translated into viral proteins. The viral DNA is replicated, and new virus particles are assembled and released from the cell.
Pathogenesis
Yatapoxviruses are known to cause disease in humans and non-human primates. The two species in the genus, Tanapox virus and Yaba monkey tumor virus, cause similar diseases characterized by skin lesions. In humans, infection with these viruses typically results in a mild, self-limiting disease.
Epidemiology
Yatapoxviruses are found in Africa and are believed to be transmitted to humans from non-human primates. The exact mode of transmission is not known, but it is thought to involve direct contact with infected animals or their bodily fluids.
Prevention and Control
There is currently no specific treatment or vaccine for Yatapoxvirus infections. Prevention measures include avoiding contact with non-human primates and practicing good hygiene.
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Contributors: Prab R. Tumpati, MD