Willebrand

Willebrand Disease

Willebrand Disease (pronounced: vil-uh-brand) is a blood clotting disorder that is often inherited. It is named after the Finnish physician Erik von Willebrand, who first described the condition in the early 20th century.

Etymology

The term "Willebrand Disease" is derived from the name of its discoverer, Dr. Erik Adolf von Willebrand. He was a Finnish physician who first described the condition in 1926.

Definition

Willebrand Disease is a lifelong bleeding disorder in which your blood doesn't clot well. People with this condition often experience extended bleeding time after an injury, surgery, or having a tooth pulled. In severe cases, heavy bleeding occurs after minor trauma or even in the absence of injury.

Symptoms

Symptoms of Willebrand Disease can vary greatly from person to person. They may include:

• Easy bruising
• Prolonged bleeding from minor cuts or abrasions
• Nosebleeds
• Bleeding gums
• Heavy or prolonged menstrual bleeding in women

Types

There are three types of Willebrand Disease:

• Type 1: This is the mildest and most common form of the disease.
• Type 2: This form of the disease is more severe and is often associated with a specific genetic mutation.
• Type 3: This is the most severe form of the disease and is often associated with a complete lack of von Willebrand factor in the blood.

Diagnosis

Diagnosis of Willebrand Disease involves a series of blood tests to measure the amount of von Willebrand factor in the blood and how well it functions. Genetic testing may also be performed to identify any mutations in the gene that produces von Willebrand factor.

Treatment

Treatment for Willebrand Disease focuses on stopping or preventing bleeding episodes, typically by using medications that increase the amount of von Willebrand factor in the blood.

Related Terms

• Blood clotting disorders
• Erik von Willebrand
• Blood tests
• Genetic testing

External links

• Medical encyclopedia article on Willebrand
• Wikipedia's article - Willebrand

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