WBRT

WBRT or Whole Brain Radiation Therapy is a type of radiation therapy used in the treatment of brain metastases, brain tumors that have spread from other parts of the body. It involves the delivery of radiation to the entire brain, and is typically used when there are multiple tumors present.

History

The use of WBRT dates back to the mid-20th century, when it was first used as a treatment for metastatic cancer. Over the years, it has been refined and improved, with advances in technology allowing for more precise delivery of radiation and better management of side effects.

Procedure

WBRT is typically delivered in multiple sessions over a period of weeks. The patient is positioned on a treatment table, and a machine delivers radiation to the entire brain. The procedure is painless, but can cause side effects such as fatigue, nausea, and hair loss.

Efficacy

Studies have shown that WBRT can be effective in controlling the growth of brain metastases, and can improve symptoms such as headaches and seizures. However, it is not a cure for metastatic cancer, and the overall survival benefit is limited.

Side Effects

Common side effects of WBRT include fatigue, nausea, and hair loss. More serious side effects can include cognitive decline, which can affect memory and thinking skills. Strategies to mitigate these side effects are an active area of research.

Alternatives

Alternatives to WBRT include stereotactic radiosurgery, which delivers a high dose of radiation to a specific area, and chemotherapy, which uses drugs to kill cancer cells. The choice of treatment depends on factors such as the number and location of tumors, and the patient's overall health.

See Also

• Radiation therapy
• Brain metastases
• Stereotactic radiosurgery
• Chemotherapy