WAY-181187

WAY-181,187.svg

WAY-181187 is a chemical compound that acts as a selective antagonist for the serotonin 5-HT6 receptor. It has been studied for its potential effects on cognition and memory, and it is of interest in the field of neuropharmacology.

Pharmacology

WAY-181187 is known for its high affinity and selectivity towards the 5-HT6 receptor, a subtype of the serotonin receptor family. The 5-HT6 receptor is predominantly found in the central nervous system, particularly in regions associated with learning and memory, such as the hippocampus and cortex.

Mechanism of Action

As a 5-HT6 receptor antagonist, WAY-181187 works by blocking the action of serotonin at this receptor site. This blockade can lead to an increase in the release of other neurotransmitters, such as acetylcholine, dopamine, and glutamate, which are crucial for cognitive processes.

Research and Potential Applications

Research on WAY-181187 has shown promise in improving cognitive functions in animal models. Studies suggest that it may enhance memory and learning abilities, making it a potential candidate for the treatment of cognitive disorders such as Alzheimer's disease and schizophrenia.

Safety and Side Effects

The safety profile of WAY-181187 is still under investigation. As with any pharmacological agent, it is essential to conduct thorough clinical trials to determine its safety and efficacy in humans.

See Also

• Serotonin receptor
• 5-HT6 receptor
• Neuropharmacology
• Cognitive enhancer

External Links

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