Volinanserin
Volinanserin
Volinanserin (pronounced vo-lin-an-ser-in) is a type of antagonist that is selective for the serotonin 5-HT2A receptor. It was developed by Actelion and has been used in scientific research to help understand the function of the 5-HT2A receptor.
Etymology
The name "Volinanserin" is derived from the Latin "volitant", meaning "flying", and "serin", a reference to the serotonin receptor it targets.
Pharmacology
Volinanserin is a potent and selective antagonist for the 5-HT2A receptor, a type of G protein-coupled receptor that is activated by the neurotransmitter serotonin. By blocking the activity of this receptor, Volinanserin can modulate the effects of serotonin in the brain.
Clinical Use
While Volinanserin has not been approved for clinical use, it has been used in scientific research to study the role of the 5-HT2A receptor in various neurological and psychiatric disorders, including schizophrenia, depression, and anxiety.
Related Terms
- Antagonist: A substance that interferes with or inhibits the physiological action of another.
- Serotonin: A compound present in blood platelets and serum, which constricts the blood vessels and acts as a neurotransmitter.
- 5-HT2A receptor: A subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor.
- G protein-coupled receptor: A large protein family of receptors that sense molecules outside the cell and activate inside signal transduction pathways.
- Actelion: A pharmaceutical company that specializes in the discovery, development and commercialization of innovative drugs for diseases with significant unmet medical needs.
External links
- Medical encyclopedia article on Volinanserin
- Wikipedia's article - Volinanserin
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