Vildagliptin/metformin

From WikiMD's medical encyclopedia

Vildagliptin/Metformin is a combination medication used in the treatment of Type 2 diabetes. It contains two active ingredients, Vildagliptin and Metformin, which work together to control blood sugar levels in people with diabetes.

Overview

Vildagliptin is a Dipeptidyl peptidase-4 inhibitor (DPP-4 inhibitor) which works by increasing the amount of insulin produced by the body and reducing the amount of glucose produced by the liver. Metformin is a Biguanide which works by decreasing glucose production in the liver and increasing the body's sensitivity to insulin.

Uses

Vildagliptin/Metformin is used in the treatment of Type 2 diabetes. It is used when diet and exercise alone does not provide adequate control of blood sugar levels. It may be used alone or in combination with other diabetes medications.

Side Effects

Common side effects of Vildagliptin/Metformin include nausea, diarrhea, and abdominal pain. Serious side effects may include lactic acidosis, pancreatitis, and heart failure.

Precautions

Before taking Vildagliptin/Metformin, tell your doctor if you have kidney disease, liver disease, or a history of heart disease. This medication should not be used during pregnancy or breastfeeding without the advice of a doctor.

Interactions

Vildagliptin/Metformin may interact with other medications, including other diabetes medications, blood pressure medications, and certain antibiotics. Always tell your doctor about any other medications you are taking.

Dosage

The dosage of Vildagliptin/Metformin will depend on the individual's condition and response to treatment. It is usually taken once or twice a day with meals.

See Also

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Contributors: Prab R. Tumpati, MD