Vesicular monoamine transporter

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Vesicular Monoamine Transporter (VMAT)

Vesicular Monoamine Transporter (VMAT) is a type of transport protein that is responsible for the uptake of monoamines into vesicles in the cytoplasm of neurons and endocrine cells.

Pronunciation

Vesicular Monoamine Transporter is pronounced as vesi-kyu-lar mono-amine trans-porter.

Etymology

The term "Vesicular Monoamine Transporter" is derived from its function. "Vesicular" refers to the small sacs or vesicles in which the transporter operates. "Monoamine" refers to the type of neurotransmitters it transports, which include dopamine, norepinephrine, and serotonin. "Transporter" refers to the protein's role in moving these neurotransmitters into the vesicles.

Function

The primary function of the Vesicular Monoamine Transporter is to transport monoamines from the cytoplasm of the neuron into the vesicles. This process is essential for the storage and later release of neurotransmitters.

Types

There are two types of Vesicular Monoamine Transporters: VMAT1 and VMAT2. VMAT1 is primarily found in large dense-core vesicles in the peripheral endocrine cells, while VMAT2 is primarily found in small synaptic vesicles in the central and peripheral neurons.

Related Terms

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