Unicentric Castleman disease
Unicentric Castleman disease
Unicentric Castleman disease (pronounced: yoo-ni-sen-trik kas-ul-muhn di-zeez) is a rare, non-cancerous lymphoproliferative disorder that affects a single lymph node or a single cluster of lymph nodes. The disease is named after Dr. Benjamin Castleman, who first described it in 1956.
Etymology
The term "unicentric" is derived from the Latin uni- meaning "one" and centrum meaning "center". This refers to the disease affecting a single lymph node or a single cluster of lymph nodes. "Castleman" is the surname of the doctor who first described the disease.
Symptoms
Symptoms of unicentric Castleman disease may include fever, night sweats, fatigue, and weight loss. However, many people with unicentric Castleman disease do not have any symptoms.
Diagnosis
Diagnosis of unicentric Castleman disease typically involves a physical examination, blood tests, and imaging tests such as computed tomography (CT) scan or magnetic resonance imaging (MRI). A biopsy of the affected lymph node may also be performed.
Treatment
Treatment for unicentric Castleman disease usually involves surgical removal of the affected lymph node. In some cases, radiation therapy may also be used.
Prognosis
The prognosis for unicentric Castleman disease is generally good, especially if the disease is diagnosed early and treated promptly.
Related Terms
- Multicentric Castleman disease: A more severe form of Castleman disease that affects multiple lymph nodes and can cause systemic symptoms.
- Lymph node: A small, bean-shaped structure that is part of the body's immune system.
- Lymphoproliferative disorder: A condition in which lymphocytes are produced in excessive quantities.
External links
- Medical encyclopedia article on Unicentric Castleman disease
- Wikipedia's article - Unicentric Castleman disease
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