Troxipide

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Troxipide

Chemical structure of Troxipide

Troxipide is a pharmaceutical drug used primarily for its gastroprotective properties. It is commonly prescribed for the treatment of gastritis and other related gastrointestinal disorders. Troxipide works by enhancing the protective mechanisms of the gastric mucosa and reducing inflammation.

Mechanism of Action

Troxipide exerts its effects by modulating the production of prostaglandins in the gastric mucosa. It enhances the secretion of protective mucus and bicarbonate, which helps to maintain the integrity of the gastric lining. Additionally, Troxipide has anti-inflammatory properties that reduce the infiltration of inflammatory cells into the gastric tissue.

Pharmacokinetics

Troxipide is administered orally and is absorbed in the gastrointestinal tract. It undergoes hepatic metabolism and is excreted primarily through the kidneys. The drug has a relatively short half-life, which necessitates multiple daily doses to maintain therapeutic levels.

Clinical Uses

Troxipide is indicated for the treatment of:

It is often used in combination with other medications to enhance its therapeutic effects and to provide comprehensive management of gastrointestinal conditions.

Side Effects

Common side effects of Troxipide include:

These side effects are generally mild and transient. However, patients are advised to report any severe or persistent adverse effects to their healthcare provider.

Contraindications

Troxipide is contraindicated in patients with:

Caution is advised when prescribing Troxipide to patients with hepatic impairment.

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Contributors: Prab R. Tumpati, MD