Trientine hydrochloride
Trientine Hydrochloride
Trientine hydrochloride (pronunciation: try-EN-teen HY-droh-KLOR-ide) is a medication used primarily in the treatment of Wilson's disease, a rare inherited disorder that causes copper to accumulate in the body's organs.
Etymology
The name "trientine" is derived from the Greek word "tri" meaning three and "entine" referring to the three nitrogen atoms in the molecule. The term "hydrochloride" refers to the hydrochloric acid salt form of the drug.
Pharmacology
Trientine hydrochloride is a chelating agent that binds to copper and forms a stable complex, which is then excreted from the body. This reduces the amount of copper in the body and helps to alleviate the symptoms of Wilson's disease.
Usage
Trientine hydrochloride is used when treatment with D-penicillamine, the first-line treatment for Wilson's disease, is not possible or causes severe side effects. It may also be used in combination with other treatments for Wilson's disease.
Side Effects
Common side effects of trientine hydrochloride include nausea, vomiting, and diarrhea. Less common side effects can include anemia, lupus-like syndrome, and neurological symptoms.
Related Terms
See Also
External links
- Medical encyclopedia article on Trientine hydrochloride
- Wikipedia's article - Trientine hydrochloride
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