Transplant glomerulopathy
Transplant Glomerulopathy (trans-plant glo-mer-u-lo-pa-thy) is a pathological condition that affects the glomerulus of the kidney, often seen in patients who have undergone a kidney transplant.
Etymology
The term "Transplant Glomerulopathy" is derived from three words: "Transplant", referring to the transfer of an organ from one body to another; "Glomerulo", referring to the glomerulus, a network of tiny blood vessels in the kidney; and "Pathy", a suffix derived from the Greek word "pathos", meaning suffering or disease.
Definition
Transplant Glomerulopathy is a form of chronic allograft nephropathy, characterized by double contouring of the glomerular basement membrane, mesangial expansion, and mononuclear cell interposition. It is a significant cause of graft loss in kidney transplant recipients.
Symptoms
The symptoms of Transplant Glomerulopathy may include proteinuria, reduced glomerular filtration rate, and progressive renal dysfunction.
Diagnosis
Diagnosis of Transplant Glomerulopathy is typically made through a renal biopsy, which allows for microscopic examination of the kidney tissue.
Treatment
Treatment options for Transplant Glomerulopathy are limited and often involve managing the symptoms and slowing the progression of the disease. This may include the use of immunosuppressive therapy and treatment of co-existing conditions such as hypertension and proteinuria.
Related Terms
- Glomerulus
- Kidney transplant
- Allograft
- Proteinuria
- Glomerular filtration rate
- Renal biopsy
- Immunosuppressive therapy
External links
- Medical encyclopedia article on Transplant glomerulopathy
- Wikipedia's article - Transplant glomerulopathy
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