Betatorquevirus

Betatorquevirus is a genus of viruses in the family Anelloviridae. Viruses in Betatorquevirus are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 17-20 nm. Genomes are circular, around 2.1-3.9kb in length. The genus was first identified in 2005.

Taxonomy

The genus contains the following species:

• Betatorquevirus 1
• Betatorquevirus 2
• Betatorquevirus 3
• Betatorquevirus 4
• Betatorquevirus 5
• Betatorquevirus 6

Structure

Viruses in Betatorquevirus are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 17-20 nm. The genome is circular, around 2.1-3.9kb in length.

Life Cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the ssDNA rolling circle model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export, and budding. Humans and pigs serve as the natural host.

Clinical

Betatorquevirus is often found in healthy individuals, but has been associated with some diseases. It has been found in higher concentrations in individuals with Hepatitis, HIV, and Autoimmune diseases. However, the role of Betatorquevirus in these diseases is not yet fully understood.

External links

• NCBI Taxonomy Browser (Betatorquevirus)