Thumbprint sign

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Thumbprint sign
X-ray showing the thumbprint sign
Synonyms
Pronounce
Specialty	Radiology, Otolaryngology
Symptoms	Swelling of the epiglottis
Complications	Airway obstruction
Onset
Duration
Types
Causes	Epiglottitis, bacterial infection
Risks
Diagnosis	Lateral neck X-ray
Differential diagnosis
Prevention
Treatment	Antibiotics, airway management
Medication
Prognosis
Frequency
Deaths

The thumbprint sign is a radiological finding that is often associated with epiglottitis, a potentially life-threatening condition characterized by inflammation of the epiglottis. This sign is typically observed on a lateral neck X-ray and is indicative of swelling in the region of the epiglottis.

Pathophysiology

The thumbprint sign is named for its resemblance to the shape of a human thumbprint. It occurs due to the thickening and edema of the epiglottis, which causes it to protrude and appear enlarged on radiographic images. This swelling can obstruct the airway, leading to respiratory distress, which is why prompt recognition and treatment are critical.

Clinical Presentation

Patients with epiglottitis often present with symptoms such as sore throat, fever, difficulty swallowing (dysphagia), drooling, and stridor. The condition is more common in children but can also occur in adults. The thumbprint sign is a key diagnostic feature that helps differentiate epiglottitis from other causes of upper airway obstruction.

Radiological Appearance

On a lateral neck X-ray, the thumbprint sign appears as a rounded, thumb-like projection at the level of the epiglottis. This finding is contrasted with the normal, thin appearance of the epiglottis. The presence of the thumbprint sign should prompt immediate medical evaluation and intervention.

Management

The management of epiglottitis involves securing the airway, often through intubation, and administering appropriate antibiotics to treat the underlying infection. In severe cases, surgical intervention may be necessary to relieve the obstruction.

Differential Diagnosis

The thumbprint sign should be distinguished from other radiological signs that indicate different conditions. For example, the "steeple sign" is associated with croup, another cause of upper airway obstruction in children. Accurate diagnosis is essential for effective treatment.

See also

• Epiglottitis
• X-ray
• Airway obstruction
• Radiology