Thin basement membrane disease

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Thin basement membrane disease

Thin basement membrane disease (== Template:IPA ==

The Template:IPA (International Phonetic Alphabet) is a system of phonetic notation based primarily on the Latin alphabet. It was devised by the International Phonetic Association in the late 19th century as a standardized representation of the sounds of spoken language.

Pronunciation

The pronunciation of the term "IPA" is /aɪ piː eɪ/ in English.

Etymology

The term "IPA" is an acronym for the International Phonetic Alphabet. The International Phonetic Association, founded in 1886, created the IPA to provide a single, universal system for the transcription of spoken language.

Related Terms

  • Phonetic notation: A system used to visually represent the sounds of speech. The IPA is one type of phonetic notation.
  • Phonetics: The study of the physical sounds of human speech. It is concerned with the physical properties of speech sounds (phonemes), and the processes of their physiological production, auditory reception, and neurophysiological perception.
  • Phonology: The study of the way sounds function within a particular language or languages. While phonetics concerns the physical production, acoustic transmission and perception of the sounds of speech, phonology describes the way sounds function within a particular language or languages.
  • Transcription (linguistics): The systematic representation of spoken language in written form. The source of the words transcribe and transcription, the term means "to write across" in Latin, and it's the process of converting spoken language into written form. In linguistics, this is often done using the IPA.

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Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski), also known as benign familial hematuria and thin basement membrane nephropathy, is a genetic disorder that affects the kidneys.

Etymology

The term "thin basement membrane disease" is derived from the characteristic thinning of the glomerular basement membrane (GBM) observed in this condition. The term "benign familial hematuria" reflects the fact that this condition is often inherited and typically presents with hematuria (blood in the urine), but does not generally progress to kidney failure.

Definition

Thin basement membrane disease is a condition characterized by microscopic hematuria, minimal proteinuria, and a uniformly thin GBM. The disease is usually benign, with most individuals maintaining normal kidney function throughout their lives.

Symptoms

The most common symptom of thin basement membrane disease is hematuria. Other symptoms may include proteinuria (excess protein in the urine), hypertension (high blood pressure), and in rare cases, progressive kidney disease.

Diagnosis

Diagnosis of thin basement membrane disease is typically made through a kidney biopsy, which reveals a thinning of the GBM. Genetic testing may also be used to confirm the diagnosis.

Treatment

There is currently no specific treatment for thin basement membrane disease. Management of the condition typically involves monitoring kidney function and treating symptoms as they arise.

Related Terms

External links

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