Tezacitabine

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Tezacitabine

Tezacitabine (pronounced tez-a-sit-a-been) is a nucleoside analogue that is used in the treatment of certain types of cancer. It is a cytotoxic agent that works by inhibiting the synthesis of DNA, thereby preventing the growth and proliferation of cancer cells.

Etymology

The name "Tezacitabine" is derived from the chemical structure of the drug. The prefix "Teza-" is derived from the Greek word "teza" meaning "to cut", referring to the drug's ability to inhibit DNA synthesis. The suffix "-citabine" is a common suffix used in the names of nucleoside analogues.

Usage

Tezacitabine is used in the treatment of various types of cancer, including leukemia, lymphoma, and certain solid tumors. It is usually administered intravenously.

Mechanism of Action

Tezacitabine works by inhibiting the enzyme DNA polymerase, which is necessary for the synthesis of DNA. By inhibiting this enzyme, the drug prevents the growth and proliferation of cancer cells.

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