Testosterone decanoate

Testosterone decanoate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men.^[1] It is also used in hormone therapy for transgender men.^[2] It is given by injection into muscle usually once every one to four weeks.^[3]

Medical uses

Testosterone decanoate is used primarily in androgen replacement therapy. It is specifically used to treat hypogonadism in men, which results in low testosterone levels.^[4] It is also used in hormone therapy for transgender men.^[5]

Side effects

Side effects of testosterone decanoate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire.^[6] The drug is a controlled substance, specifically a Schedule III controlled substance, which means it has a potential for abuse and dependence.^[7]

Pharmacology

As an AAS, testosterone decanoate is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).^[8] It has strong anabolic effects and weak androgenic effects, which give it a mild side effect profile and make it especially suitable for use in women.^[9]

References

↑ Testosterone Decanoate - an overview(link). {{{website}}}. Accessed 2021-09-30.
↑ Testosterone therapy in transgender men(link). {{{website}}}. Accessed 2021-09-30.
↑ Testosterone Decanoate(link). {{{website}}}. Accessed 2021-09-30.
↑ Testosterone therapy in men with hypogonadism(link). {{{website}}}. Accessed 2021-09-30.
↑ Testosterone therapy in transgender men(link). {{{website}}}. Accessed 2021-09-30.
↑ Testosterone therapy: Potential benefits and risks as you age(link). {{{website}}}. Accessed 2021-09-30.
↑ Controlled Substances - Alphabetical Order(link). {{{website}}}. Accessed 2021-09-30.
↑ Androgen receptor(link). {{{website}}}. Accessed 2021-09-30.
↑ Anabolic steroids(link). {{{website}}}. Accessed 2021-09-30.

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[1] Testosterone Decanoate - an overview(link). {{{website}}}. Accessed 2021-09-30.

[2] Testosterone therapy in transgender men(link). {{{website}}}. Accessed 2021-09-30.

[3] Testosterone Decanoate(link). {{{website}}}. Accessed 2021-09-30.

[4] Testosterone therapy in men with hypogonadism(link). {{{website}}}. Accessed 2021-09-30.

[5] Testosterone therapy in transgender men(link). {{{website}}}. Accessed 2021-09-30.

[6] Testosterone therapy: Potential benefits and risks as you age(link). {{{website}}}. Accessed 2021-09-30.

[7] Controlled Substances - Alphabetical Order(link). {{{website}}}. Accessed 2021-09-30.

[8] Androgen receptor(link). {{{website}}}. Accessed 2021-09-30.

[9] Anabolic steroids(link). {{{website}}}. Accessed 2021-09-30.

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