Targetoid
Targetoid Lesions
Targetoid lesions are a type of skin lesion characterized by a central zone of necrosis or blistering, surrounded by concentric rings of erythema and edema. These lesions are often associated with various dermatological conditions and can be indicative of underlying systemic diseases.
Characteristics
Targetoid lesions typically present as round or oval shapes with a central area that may appear darker or necrotic. The surrounding rings can vary in color, often displaying a gradient from red to purple. The appearance of these lesions is reminiscent of a target or bullseye, hence the name "targetoid."
Associated Conditions
Targetoid lesions are commonly associated with the following conditions:
- Erythema multiforme: A hypersensitivity reaction often triggered by infections or medications, characterized by the presence of target lesions.
- Stevens-Johnson syndrome: A severe mucocutaneous reaction that can present with targetoid lesions among other symptoms.
- Lyme disease: The classic "bullseye" rash, or erythema migrans, is a type of targetoid lesion associated with this tick-borne illness.
- Fixed drug eruption: A localized skin reaction to a medication that can result in targetoid lesions upon re-exposure.
Diagnosis
The diagnosis of targetoid lesions involves a thorough clinical examination and patient history. Dermatologists may perform a skin biopsy to confirm the diagnosis and rule out other conditions. Identifying the underlying cause is crucial for effective management and treatment.
Treatment
Treatment of targetoid lesions depends on the underlying cause. For example, in cases of erythema multiforme, removing the triggering factor and providing supportive care is essential. In drug-induced cases, discontinuation of the offending medication is necessary. Systemic treatments may include corticosteroids or immunosuppressive agents in severe cases.
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Contributors: Prab R. Tumpati, MD