Superficial siderosis
Superficial siderosis
Superficial siderosis (pronunciation: soo-per-fish-ul side-roh-sis) is a rare neurological disorder characterized by the deposition of hemosiderin, a form of iron, on the surface of the brain and spinal cord.
Etymology
The term "superficial siderosis" is derived from the Latin word "superficialis" meaning "on the surface", and the Greek word "siderosis" meaning "iron condition".
Definition
Superficial siderosis is a condition that results from chronic or recurrent bleeding into the subarachnoid space, which leads to the deposition of hemosiderin in the leptomeninges and subpial layers of the brain and spinal cord. This deposition can cause progressive neurological damage.
Symptoms
The symptoms of superficial siderosis vary depending on the location and extent of hemosiderin deposition. Common symptoms include sensorineural hearing loss, ataxia, and pyramidal signs. Other symptoms may include dysphagia, nystagmus, and neuropathy.
Diagnosis
Diagnosis of superficial siderosis is typically made through magnetic resonance imaging (MRI), which can reveal the characteristic hemosiderin deposits. Other diagnostic tools may include lumbar puncture and cerebrospinal fluid analysis.
Treatment
Treatment for superficial siderosis is primarily aimed at stopping or reducing the source of bleeding. This may involve surgical intervention, or the use of iron chelation therapy to help remove excess iron from the body.
Prognosis
The prognosis for individuals with superficial siderosis varies. Some individuals may experience a slow progression of symptoms over many years, while others may experience a more rapid decline in neurological function.
See also
External links
- Medical encyclopedia article on Superficial siderosis
- Wikipedia's article - Superficial siderosis
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