Subfornical organ

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Subfornical Organ

The Subfornical Organ (SFO) (/sʌbˈfɔːrnɪkəl ˈɔːrɡən/), is a small, specialized structure in the brain that plays a crucial role in the regulation of body fluids and cardiovascular function.

Etymology

The term "Subfornical Organ" is derived from its anatomical location. The prefix "sub-" is from Latin, meaning "under" or "beneath", and "fornix" is Latin for "arch". The organ is located beneath the fornix in the brain.

Function

The Subfornical Organ is one of the circumventricular organs in the brain, which are characterized by their extensive vascularization and lack of a blood-brain barrier. This allows the SFO to sense changes in the composition of body fluids and respond accordingly. It is involved in a variety of physiological processes, including thirst, salt appetite, and cardiovascular regulation.

Anatomy

The Subfornical Organ is located in the lateral ventricle of the brain, beneath the fornix. It is a small, oval structure that is highly vascularized, allowing it to sense changes in the composition of the blood.

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