Sterility
Sterility refers to the inability of an organism to reproduce. In humans, it is often used to refer to the inability of a person to conceive or induce conception. Sterility can be due to a variety of causes, both genetic and environmental, and can affect both males and females.
Causes
Sterility can be caused by a variety of factors, including genetic abnormalities, hormonal imbalances, physical abnormalities, and environmental factors.
Genetic Causes
Genetic causes of sterility can include chromosomal abnormalities, such as Turner syndrome in females and Klinefelter syndrome in males. These conditions can result in the absence or malfunction of reproductive organs, leading to sterility.
Hormonal Causes
Hormonal imbalances can also lead to sterility. For example, conditions such as Polycystic ovary syndrome (PCOS) in women and Hypogonadism in men can disrupt the normal functioning of the reproductive system, leading to sterility.
Physical Causes
Physical abnormalities, such as blockages in the reproductive tract, can also cause sterility. This can be due to congenital abnormalities, injury, or disease.
Environmental Causes
Environmental factors, such as exposure to certain chemicals or radiation, can also cause sterility. This is often reversible once the exposure is removed.
Treatment
Treatment for sterility depends on the underlying cause. This can range from hormone therapy to surgical intervention. In some cases, assisted reproductive technologies, such as In vitro fertilization (IVF), may be used.
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Contributors: Prab R. Tumpati, MD