Skin manifestations of sarcoidosis

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Skin manifestations of sarcoidosis
Cutaneous findings in systemic sarcoidosis.JPEG
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Skin lesions, erythema nodosum, lupus pernio, maculopapular rash
Complications Scarring, disfigurement, psychosocial impact
Onset Variable
Duration Chronic
Types N/A
Causes Sarcoidosis
Risks African American descent, female gender, family history
Diagnosis Clinical examination, biopsy, imaging studies
Differential diagnosis Lupus erythematosus, granuloma annulare, lichen planus
Prevention N/A
Treatment Corticosteroids, immunosuppressive therapy, antimalarials
Medication N/A
Prognosis Variable, often chronic
Frequency Common in sarcoidosis patients
Deaths N/A


Skin manifestations of sarcoidosis

Sarcoidosis is a systemic inflammatory disease that can affect any organ in the body, including the skin. Skin manifestations of sarcoidosis are diverse and can be the first sign of the disease.

Introduction

Sarcoidosis is a disease characterized by the formation of granulomas, small collections of inflammatory cells, in different parts of the body. When these granulomas form in the skin, they can cause a variety of skin manifestations.

Types of Skin Manifestations

Erythema Nodosum

Erythema nodosum is a common skin manifestation of sarcoidosis. It is characterized by tender, red nodules that usually appear on the shins.

Lupus Pernio

Lupus pernio is a specific skin manifestation of sarcoidosis that is characterized by purple or red bumps or lesions on the nose, cheeks, and ears.

Plaque Sarcoidosis

Plaque sarcoidosis is characterized by raised, red, and often scaly patches on the skin. It can occur anywhere on the body but is most common on the extremities.

Nodular Sarcoidosis

Nodular sarcoidosis is characterized by firm, flesh-colored or red nodules that can occur anywhere on the body.

Diagnosis

Diagnosis of skin manifestations of sarcoidosis is typically made through a combination of clinical examination, biopsy, and other tests as needed.

Treatment

Treatment for skin manifestations of sarcoidosis typically involves corticosteroids, either applied topically or taken orally. Other treatments may include antimalarial drugs, methotrexate, or tumor necrosis factor inhibitors.

Conclusion

Skin manifestations of sarcoidosis are diverse and can be the first sign of the disease. Early recognition and treatment can help to prevent complications and improve quality of life for patients with this condition.

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Contributors: Prab R. Tumpati, MD