Senolytic
Senolytic
Senolytic (pronunciation: /sɛnəˈlɪtɪk/) is a term used in the field of gerontology and biomedical research to describe a type of drug that selectively induces apoptosis, or programmed cell death, in senescent cells.
Etymology
The term "senolytic" is derived from the words "senescence," which refers to the state of cell aging, and "lytic," which means to destroy or break down.
Definition
Senolytics are a class of small molecules under basic research to determine if they can selectively induce death of senescent cells and improve health in humans. Their main mechanism of action is the induction of apoptosis in senescent cells, which are cells that have stopped dividing and accumulate with age, contributing to aging and age-related diseases.
Related Terms
- Senescence: The condition or process of deterioration with age.
- Apoptosis: A form of programmed cell death that occurs in multicellular organisms.
- Autophagy: The natural, regulated mechanism of the cell that removes unnecessary or dysfunctional components.
- Cellular Senescence: A state of stable cell cycle arrest and a response to various forms of stress.
- Gerontology: The study of the social, cultural, psychological, cognitive, and biological aspects of aging.
See Also
External links
- Medical encyclopedia article on Senolytic
- Wikipedia's article - Senolytic
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