Scid
Scid
Scid (/skɪd/), an acronym for Severe Combined Immunodeficiency, is a genetic disorder characterized by the disturbed development of functional T cells and B cells caused by numerous genetic mutations that result in differing clinical presentations.
Etymology
The term Scid is derived from the phrase Severe Combined Immunodeficiency. The term was first used in the late 20th century to describe a condition in mice that was later found to be applicable to humans as well.
Definition
Severe Combined Immunodeficiency (Scid) is a primary immunodeficiency disorder affecting the immune system. It is characterized by a severe defect in both the T- & B-lymphocyte systems, and sometimes the Natural Killer (NK) cells as well, leading to complex immunodeficiency disease in which there is a combined absence of T-lymphocyte and B-lymphocyte function.
Symptoms
The symptoms of Scid include infections that do not improve with usual treatments, diarrhea, pneumonia, and thrush that is difficult to treat.
Diagnosis
Diagnosis of Scid is typically made through genetic testing, blood tests, and immunologic tests to evaluate the function of the immune system.
Treatment
Treatment for Scid typically involves bone marrow transplant, gene therapy, and/or enzyme replacement therapy.
Related Terms
- Immunodeficiency
- T cells
- B cells
- Natural Killer Cells
- Bone marrow transplant
- Gene therapy
- Enzyme replacement therapy
External links
- Medical encyclopedia article on Scid
- Wikipedia's article - Scid
This WikiMD article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski