SRT-1460

From WikiMD's medical encyclopedia

SRT-1460 is a pharmacological compound that is classified as a Sirtuin-activating compound (STAC). It is known for its potential therapeutic applications in various diseases and disorders, particularly those related to aging and metabolism.

Overview

SRT-1460 is a synthetic molecule that has been shown to activate sirtuin enzymes, specifically SIRT1. Sirtuins are a family of proteins that play a crucial role in cellular health, influencing processes such as DNA repair, inflammation, metabolism, and longevity. By activating these enzymes, SRT-1460 has the potential to influence these processes and potentially treat or prevent a variety of diseases.

Mechanism of Action

SRT-1460 functions by binding to the SIRT1 enzyme and enhancing its activity. This increased activity can influence a variety of cellular processes. For example, it can enhance DNA repair mechanisms, reduce inflammation, and improve metabolic function. This can potentially slow the aging process and prevent or treat a variety of age-related diseases.

Potential Therapeutic Applications

Research into the potential therapeutic applications of SRT-1460 is ongoing. However, preliminary studies suggest that it may have potential in treating a variety of conditions, including diabetes, cardiovascular disease, neurodegenerative disease, and cancer. It may also have potential in promoting longevity and healthy aging.

Safety and Side Effects

As with any pharmacological compound, SRT-1460 has the potential to cause side effects. These can vary depending on the dosage and individual patient characteristics. Potential side effects may include nausea, headache, and dizziness. More research is needed to fully understand the safety profile of SRT-1460.

Future Research

Future research into SRT-1460 will likely focus on further elucidating its mechanism of action, determining its safety and efficacy in various patient populations, and exploring its potential therapeutic applications in more detail.

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  • SRT-1460 Structure

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Contributors: Prab R. Tumpati, MD