Rheumatoid nodule

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Obesity, Sleep & Internal medicine
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Rheumatoid nodule
Histopathology of a rheumatoid nodule
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Firm lumps under the skin, usually over bony areas
Complications	Infection, ulceration
Onset	Typically occurs in patients with rheumatoid arthritis
Duration	Chronic
Types	N/A
Causes	Rheumatoid arthritis
Risks	Rheumatoid factor positivity, severe rheumatoid arthritis
Diagnosis	Clinical examination, biopsy
Differential diagnosis	Gouty tophi, lipoma, ganglion cyst
Prevention	N/A
Treatment	Methotrexate, corticosteroids, surgical removal
Medication	N/A
Prognosis	Generally benign, but may indicate severe rheumatoid arthritis
Frequency	Occurs in about 20-30% of patients with rheumatoid arthritis
Deaths	N/A

Rheumatoid nodules are firm lumps that appear under the skin near joints affected by rheumatoid arthritis. They are the most common skin manifestation of rheumatoid arthritis and are often associated with a more severe course of the disease.

Signs and Symptoms

Rheumatoid nodules are typically round or oval and range in size from a pea to a walnut. They are usually found on pressure points such as the elbows, fingers, knuckles, and the back of the heel. However, they can also occur in other areas such as the lungs and heart. The nodules are usually painless, but can become tender or painful if they become infected or ulcerated.

Causes

The exact cause of rheumatoid nodules is unknown, but they are thought to be a result of inflammation caused by rheumatoid arthritis. They are more common in people who have severe rheumatoid arthritis and those who test positive for rheumatoid factor, an antibody found in the blood of most people with rheumatoid arthritis.

Diagnosis

Rheumatoid nodules are usually diagnosed based on their appearance and location. A doctor may also perform a biopsy, where a small sample of the nodule is removed and examined under a microscope to confirm the diagnosis.

Treatment

Treatment for rheumatoid nodules is usually not necessary unless they are causing discomfort or complications. If treatment is needed, it may include medications to reduce inflammation and pain, or surgery to remove the nodules.

See Also

• Rheumatoid Arthritis
• Rheumatoid Factor
• Inflammation

References

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