Reticular erythematous mucinosis

Reticular erythematous mucinosis
Synonyms	REM syndrome
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Reticular erythematous mucinosis (REM) is a rare skin condition characterized by a reticular (net-like) pattern of erythematous (red) patches. It is primarily seen in middle-aged women and is associated with the accumulation of mucin in the dermis.

Presentation

Patients with reticular erythematous mucinosis typically present with red, net-like patches on the chest and back. These patches may be asymptomatic or associated with mild itching. The condition is chronic and may persist for many years.

Pathophysiology

The exact cause of reticular erythematous mucinosis is unknown. It is thought to be related to hormonal changes, as it predominantly affects women. The condition is characterized by the deposition of mucin in the dermis, which is a gel-like substance that can accumulate in the skin.

Diagnosis

Diagnosis of reticular erythematous mucinosis is primarily clinical, supported by a skin biopsy. The biopsy typically shows mucin deposition in the dermis and a mild perivascular lymphocytic infiltrate.

Treatment

Treatment options for reticular erythematous mucinosis include topical corticosteroids, antimalarials such as hydroxychloroquine, and phototherapy. The response to treatment can vary, and some patients may experience spontaneous resolution of the condition.

Prognosis

The prognosis for reticular erythematous mucinosis is generally good, although the condition can be persistent. It is not associated with any serious systemic complications.

See also

• Cutaneous mucinosis
• List of cutaneous conditions

External links

• Reticular erythematous mucinosis on WikiMD