Systemic
In the field of medicine, the term systemic is utilized to describe processes, diseases, or effects that impact the entire body or multiple systems within it. The term contrasts with "localized," which refers to something affecting only one part of the body. This article explores the various contexts in which "systemic" is employed in medicine.
Systemic Administration
Systemic administration pertains to a route of administration for medications designed to affect the whole body. When drugs are given systemically, they are usually introduced into the circulatory system, ensuring widespread distribution throughout the body.
Systemic Circulation
Systemic circulation is the portion of the cardiovascular system which carries oxygen-rich blood away from the heart, delivers it to the body's tissues, and subsequently transports the oxygen-depleted blood back to the heart.
Systemic Disease
A systemic disease is an illness that has effects on multiple organs, systems, or tissues. Instead of being confined to one location, the disease manifests in various parts of the body, often influencing overall health.
Systemic Effect
A systemic effect describes an adverse impact resulting from an exposure that concerns the body as a whole, rather than a singular, localized region.
Systemic Inflammatory Response Syndrome
Systemic inflammatory response syndrome (SIRS) represents a generalized inflammatory state, often triggered by infection, which affects the entire body. This condition can progress and result in widespread organ failure.
Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting connective tissues. As a systemic illness, SLE can involve any part of the body, presenting varied symptoms based on which systems are affected.
Systemic Scleroderma
Also termed systemic sclerosis, systemic scleroderma is a connective tissue disease of systemic nature. The condition leads to skin thickening and can impact internal organs.
Systemic Venous System
The systemic venous system consists of veins that transport blood to the heart's right atrium without necessitating passage through two separate vascular beds.
Systemic Exertion Intolerance Disease
Systemic exertion intolerance disease (SEID) was proposed as a name replacement for what is commonly known as chronic fatigue syndrome by the Institute of Medicine in 2015. This renaming was suggested to better encapsulate the comprehensive impact of the illness.
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Contributors: Prab R. Tumpati, MD