Pyridoxamine

From WikiMD's medical encyclopedia

Pyridoxamine is a form of vitamin B6 that is converted into pyridoxal 5'-phosphate, a coenzyme for many reactions in the body. It is found in certain foods and is also available as a dietary supplement.

Sources and Functions

Pyridoxamine is found in a variety of foods, including meat, poultry, fish, whole grains, nuts, and legumes. It is also available as a dietary supplement, often in combination with other forms of vitamin B6.

The primary function of pyridoxamine is to act as a coenzyme for many reactions in the body. These include the metabolism of amino acids, carbohydrates, and lipids. It is also involved in the synthesis of hemoglobin, the protein in red blood cells that carries oxygen throughout the body.

Health Benefits and Risks

There is evidence that pyridoxamine may have health benefits beyond its role as a coenzyme. Some studies suggest that it may help to prevent or slow the progression of certain diseases, including diabetes and kidney disease. However, more research is needed to confirm these findings and to understand the mechanisms involved.

There are also potential risks associated with pyridoxamine. High doses can cause neurological problems, including sensory neuropathy and ataxia. It can also interact with certain medications, including levodopa, a drug used to treat Parkinson's disease.

See Also

References

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Pyridoxamine

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