Pulmonary venoocclusive disease
Pulmonary Venoocclusive Disease (Pronunciation: Pul-mo-nary Vee-no-oc-clu-sive Disease) is a rare form of Pulmonary Hypertension characterized by blockage of the small veins in the lungs.
Etymology
The term "Pulmonary Venoocclusive Disease" is derived from the Latin pulmo (lung), vena (vein), occludere (to close up), and disease (dis-ease).
Definition
Pulmonary Venoocclusive Disease (PVOD) is a rare and often fatal condition that affects the small veins (venules) in the lungs, leading to pulmonary hypertension. It is characterized by the blockage (occlusion) of pulmonary venules, which leads to increased pressure in the pulmonary arteries and ultimately to heart failure.
Symptoms
The symptoms of Pulmonary Venoocclusive Disease are similar to those of other forms of Pulmonary Hypertension, and may include shortness of breath, fatigue, and fainting spells.
Causes
The exact cause of Pulmonary Venoocclusive Disease is unknown, but it may be related to exposure to certain toxins or drugs, or it may be associated with other medical conditions such as Connective Tissue Disease or HIV.
Diagnosis
Diagnosis of Pulmonary Venoocclusive Disease can be challenging due to its rarity and the nonspecific nature of its symptoms. It is often diagnosed through a process of exclusion, with other causes of pulmonary hypertension being ruled out first. Diagnostic tests may include pulmonary function tests, chest X-rays, and right heart catheterization.
Treatment
Treatment for Pulmonary Venoocclusive Disease is limited and often focuses on managing symptoms and improving quality of life. This may include medications to reduce pulmonary hypertension, oxygen therapy, and in severe cases, lung transplantation.
See Also
External links
- Medical encyclopedia article on Pulmonary venoocclusive disease
- Wikipedia's article - Pulmonary venoocclusive disease
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