Proteostasis

From WikiMD.org
Jump to navigation Jump to search

Proteostasis

Proteostasis (pronounced pro-tee-oh-stay-sis) is a term in the field of Biology and Biochemistry that refers to the regulation of the cellular protein pool. It is a portmanteau of the words "protein" and "homeostasis".

Etymology

The term "Proteostasis" is derived from the combination of "protein", a complex molecule that is essential for the structure and function of the body's cells, and "homeostasis", a term in biology that refers to the ability of an organism or cell to maintain internal equilibrium by adjusting its physiological processes.

Definition

Proteostasis involves the balance of protein synthesis, folding, translocation, and degradation. It is a critical process for cell function and survival. Disruptions in proteostasis can lead to the accumulation of misfolded proteins, which can cause a variety of diseases, including Alzheimer's disease, Parkinson's disease, and Cystic fibrosis.

Related Terms

  • Protein synthesis: The process by which cells generate new proteins.
  • Protein folding: The process by which a protein structure assumes its functional shape or conformation.
  • Protein degradation: The process by which cells break down and recycle proteins.
  • Protein homeostasis: The balance of protein synthesis and degradation to maintain cellular function.

See Also

  • Chaperone (protein): Proteins that assist in the folding of other proteins.
  • Ubiquitin: A small protein that is used to tag proteins for degradation.
  • Autophagy: The process by which cells recycle their own components, including proteins.

External links

Esculaap.svg

This WikiMD article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski