Propynyl (psychedelic)
Propynyl (psychedelic)
Propynyl is a class of psychedelic drugs that are derived from certain types of alkyne. These substances are known for their psychoactive effects, which can include altered thinking processes, closed- and open-eye visuals, synesthesia, an altered sense of time, and spiritual experiences.
History
The history of propynyl compounds as psychedelics is relatively recent, with the first known synthesis and use occurring in the late 20th century. The most well-known propynyl psychedelic is LSD, which was first synthesized in 1938 by Swiss chemist Albert Hofmann.
Chemistry
Propynyl psychedelics are characterized by a propynyl group, which is a functional group consisting of a hydrocarbon chain with a triple bond at the end. This group is attached to a larger molecule, typically a tryptamine, phenethylamine, or lysergamide. The presence of the propynyl group can significantly alter the psychoactive properties of the drug.
Pharmacology
The pharmacology of propynyl psychedelics is complex and not fully understood. However, it is known that these substances act primarily as serotonin receptor agonists. They may also interact with other neurotransmitter systems, including the dopamine and norepinephrine systems.
Effects
The effects of propynyl psychedelics can vary widely depending on the specific drug, the dose, the user's individual physiology, and the context in which the drug is used. However, common effects can include visual and auditory hallucinations, altered perception of time, enhanced introspection, and feelings of euphoria or dysphoria.
Legal status
The legal status of propynyl psychedelics varies by country and by specific drug. In many jurisdictions, these substances are classified as controlled substances, making their manufacture, sale, and use illegal without a license or prescription.
See also
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Contributors: Prab R. Tumpati, MD