Proliferating angioendotheliomatosis

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Proliferating angioendotheliomatosis
Synonyms Intravascular lymphomatosis, Intravascular large B-cell lymphoma
Pronounce N/A
Specialty N/A
Symptoms Skin lesions, neurological symptoms, fever, weight loss
Complications Organ failure, Neurological deficits
Onset Typically in adults
Duration Chronic
Types N/A
Causes Unknown, possibly related to immune system dysfunction
Risks Immunocompromised state
Diagnosis Biopsy, Immunohistochemistry
Differential diagnosis Vasculitis, Cutaneous lymphoma, Angiosarcoma
Prevention N/A
Treatment Chemotherapy, Radiation therapy
Medication N/A
Prognosis Poor, often aggressive
Frequency Rare
Deaths N/A


Proliferating angioendotheliomatosis is a rare form of vascular tumor that is characterized by the proliferation of endothelial cells. This condition is often associated with malignancy and can affect various organs in the body.

Symptoms

The symptoms of proliferating angioendtheliomatosis can vary depending on the organ affected. Common symptoms include pain, swelling, and the presence of a mass. In some cases, the condition may be asymptomatic and only discovered during routine medical examinations.

Causes

The exact cause of proliferating angioendotheliomatosis is unknown. However, it is often associated with malignancies such as lung cancer, breast cancer, and lymphoma. It is believed that the tumor cells may produce substances that stimulate the growth of endothelial cells, leading to the formation of vascular tumors.

Diagnosis

Diagnosis of proliferating angioendotheliomatosis is typically made through a combination of medical history, physical examination, and imaging studies. Biopsy of the affected tissue may also be performed to confirm the diagnosis.

Treatment

Treatment for proliferating angioendotheliomatosis typically involves the management of the underlying malignancy. This may include chemotherapy, radiation therapy, or surgery. In some cases, the vascular tumors may also need to be surgically removed.

Prognosis

The prognosis for individuals with proliferating angioendotheliomatosis is generally poor, due to the association with malignancy. However, early detection and treatment can improve the prognosis.

See also

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Contributors: Prab R. Tumpati, MD