AL amyloidosis
AL Amyloidosis
AL Amyloidosis (pronounced A-L am-uh-loi-DOH-sis), also known as Primary Amyloidosis or Light Chain Amyloidosis, is a rare disease that occurs when an abnormal protein called amyloid builds up in organs and interferes with their normal function.
Etymology
The term "Amyloidosis" is derived from the Greek words "amylon" which means starch and "osis" which refers to a condition. The "AL" in AL Amyloidosis stands for "Amyloid Light chain", indicating the type of protein involved in this condition.
Definition
AL Amyloidosis is a condition characterized by the buildup of abnormal proteins, known as Amyloid proteins, in various organs of the body. These proteins are produced by cells in the Bone Marrow and can accumulate in any tissue or organ, including the Kidney, Heart, and Liver.
Symptoms
Symptoms of AL Amyloidosis can vary widely, depending on which organs are affected. Common symptoms may include fatigue, weight loss, shortness of breath, and swelling in the legs and ankles.
Diagnosis
Diagnosis of AL Amyloidosis often involves a combination of blood tests, urine tests, imaging studies, and sometimes a tissue biopsy. The presence of Monoclonal Protein or light chains in the blood or urine can suggest AL Amyloidosis.
Treatment
Treatment for AL Amyloidosis aims to limit the production of amyloid protein and manage symptoms. This may involve chemotherapy, stem cell transplant, or supportive care to manage symptoms and organ function.
Prognosis
The prognosis for AL Amyloidosis can vary widely, depending on the organs involved and the extent of organ damage. Early detection and treatment can improve the prognosis.
Related Terms
External links
- Medical encyclopedia article on AL amyloidosis
- Wikipedia's article - AL amyloidosis
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